In situ formation of nanofibers from purpurin18-peptide conjugates and the assembly induced retention effect in tumor sites
文献类型：期刊论文
| 作者 | Zhang, Di; Qi, Guo-Bin; Zhao, Ying-Xi; Qiao, Sheng-Lin; Yang, Chao; Wang, Hao |
| 刊名 | Advanced materials
 |
| 出版日期 | 2015-10-28 |
| 卷号 | 27期号:40页码:6125-6130 |
| 关键词 | Chlorophyll Nanomaterials Photoacoustic imaging Supramolecular structures Tumor therapies |
| ISSN号 | 0935-9648 |
| DOI | 10.1002/adma.201502598 |
| 通讯作者 | Wang, hao(wanghao@nanoctr.cn) |
| 英文摘要 | An assembly-induced retention effect for enhanced tumor photoacoustic (pa) imaging and therapeutics is described. a responsive small-molecule precursor is prepared that simultaneously self-assembles into nanofibers in tumor sites that exhibit an assembly-induced retention effect, which results in an improved pa imaging signal and enhanced therapeutic efficacy. this successful proof-of-concept study paves the way to develop novel supramolecular biomaterials for cancer diagnostics and therapeutics. |
| WOS关键词 | INTRACELLULAR DRUG-DELIVERY ; IMAGING PROBES ; POLYMERIC NANOPARTICLES ; CONTRAST AGENTS ; CANCER-THERAPY ; VIVO ; DESIGN ; CELLS ; ORGANIZATION ; METASTASIS |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 语种 | 英语 |
| WOS记录号 | WOS:000363476200007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176478 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Wang, Hao |
| 作者单位 | Natl Ctr Nanosci & Technol NCNST, Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Di,Qi, Guo-Bin,Zhao, Ying-Xi,et al. In situ formation of nanofibers from purpurin18-peptide conjugates and the assembly induced retention effect in tumor sites[J]. Advanced materials,2015,27(40):6125-6130. |
| APA | Zhang, Di,Qi, Guo-Bin,Zhao, Ying-Xi,Qiao, Sheng-Lin,Yang, Chao,&Wang, Hao.(2015).In situ formation of nanofibers from purpurin18-peptide conjugates and the assembly induced retention effect in tumor sites.Advanced materials,27(40),6125-6130. |
| MLA | Zhang, Di,et al."In situ formation of nanofibers from purpurin18-peptide conjugates and the assembly induced retention effect in tumor sites".Advanced materials 27.40(2015):6125-6130. |
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来源：高能物理研究所
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