Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels
文献类型：期刊论文
| 作者 | Liu, Kun1; Hao, Ming1; Meng, Donghui2; Wan, Xujie3; Xiao, Songwen4; Sun, Songgang1; Wang, Dongyang1; Ba, Dechun1 |
| 刊名 | Journal of new materials for electrochemical systems
 |
| 出版日期 | 2015-10-01 |
| 卷号 | 18期号:4页码:243-249 |
| 关键词 | Nanofluidics Biological chip Molecular dynamics Wet chemical etching |
| ISSN号 | 1480-2422 |
| 通讯作者 | Liu, kun(kliu@mail.neu.edu.cn) |
| 英文摘要 | As the size of microfluidic channel further shrinks to nanometer, the dimension is approximate to biomolecules as well as de bye length (dl). great deals of phenomena which do not exist in the usual world will appear. the overlapping of electrical double layers (edl) in the channel and the increasing of the viscosity are such good examples. all of these phenomena lead to the fundamental research such as colloid science, transport process and micro/nanoscale hydrodynamics. it demands more advanced technique for micro/nanoscale design and fabrication as the channels downing to nanometer scale. in this work, molecular dynamics was adopted to calculate the transport of proteins and water molecules in nanofluidic channels. new methods of nanochannel fabrication were developed based on glass substrate. glass nanochips were achieved via ultraviolet lithography and wet chemical etching. the channel depth could be adjusted by controlling the etching time. finally the scanning electron microscope (sem) and surface profiler were used to characterize the shape and surface morphology of the nanochannel in detail. this study presents the feasibility of such design and fabrication methods, which gives an interesting exploration for the application of nanofluidic technology. |
| WOS关键词 | LONG DNA-MOLECULES ; NANOCHANNELS ; SEPARATION ; DIFFUSION ; TRANSPORT ; PROTEINS ; DEVICES ; FIELD ; CHIPS |
| WOS研究方向 | Electrochemistry ; Materials Science |
| WOS类目 | Electrochemistry ; Materials Science, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000381248700009 |
| 出版者 | ECOLE POLYTECHNIQUE MONTREAL |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176590 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Liu, Kun |
| 作者单位 | 1.Northeastern Univ, Sch Mech Engn & Automat, 3-11 Wenhua Rd, Shenyang 110004, Peoples R China 2.Beijing Inst Spacecraft Environm Engn, Beijing 100094, Peoples R China 3.China Aviat Ind Grp Co LTD, Beijing Inst Aviat Mat, Beijing 100095, Peoples R China 4.Chinese Acad Sci, Inst High Energy Phys, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Kun,Hao, Ming,Meng, Donghui,et al. Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels[J]. Journal of new materials for electrochemical systems,2015,18(4):243-249. |
| APA | Liu, Kun.,Hao, Ming.,Meng, Donghui.,Wan, Xujie.,Xiao, Songwen.,...&Ba, Dechun.(2015).Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels.Journal of new materials for electrochemical systems,18(4),243-249. |
| MLA | Liu, Kun,et al."Investigation on the electrochemical manipulation of bio-molecules in glass nanofluidic channels".Journal of new materials for electrochemical systems 18.4(2015):243-249. |
入库方式： iSwitch采集
来源：高能物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。