Polymers with tertiary amine groups for drug delivery and bioimaging
文献类型：期刊论文
| 作者 | Gao, Yu-Juan; Qiao, Zeng-Ying; Wang, Hao |
| 刊名 | Science china-chemistry
 |
| 出版日期 | 2016-08-01 |
| 卷号 | 59期号:8页码:991-1002 |
| 关键词 | Biopolymers Tertiary amine groups Ph-responsive Drug delivery Bioimaging |
| ISSN号 | 1674-7291 |
| DOI | 10.1007/s11426-015-0516-2 |
| 通讯作者 | Wang, hao(wanghao@nanoctr.cn) |
| 英文摘要 | Over the past decade, biopolymers have gained great interests especially in biomedicine due to their physical properties and/or chemical structures changes in response to external stimuli in a certain time frame or at a specific location. among them, poly(beta-amino ester)s, methacrylate-based block copolymers and polypeptide with tertiary amine groups have been extensively studied and exhibit ph sensitive properties due to the protonation of tertiary amine groups. the ph values in normal organs, tissues, and subcellular compartments are always different from those in pathological tissues. these interesting properties allow their applications in a variety of fields ranging from diagnosis and therapeutics of diseases. here, we review the recent progress of poly(beta-amino ester)s, methacrylate-based block copolymers and polypeptide with tertiary amine groups and their applications in drug delivery and bioimaging. |
| WOS关键词 | BLOCK-COPOLYMER MICELLES ; POLY(BETA-AMINO ESTER) NANOPARTICLES ; PH-RESPONSIVE NANOPARTICLES ; TUMOR-TARGETED DELIVERY ; CANCER-THERAPY ; IN-VIVO ; HYDROPHOBIC DRUGS ; SENSITIVE SYSTEM ; STIMULI ; RELEASE |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000380684000010 |
| 出版者 | SCIENCE PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176591 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Wang, Hao |
| 作者单位 | Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gao, Yu-Juan,Qiao, Zeng-Ying,Wang, Hao. Polymers with tertiary amine groups for drug delivery and bioimaging[J]. Science china-chemistry,2016,59(8):991-1002. |
| APA | Gao, Yu-Juan,Qiao, Zeng-Ying,&Wang, Hao.(2016).Polymers with tertiary amine groups for drug delivery and bioimaging.Science china-chemistry,59(8),991-1002. |
| MLA | Gao, Yu-Juan,et al."Polymers with tertiary amine groups for drug delivery and bioimaging".Science china-chemistry 59.8(2016):991-1002. |
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来源：高能物理研究所
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