Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation
文献类型：期刊论文
| 作者 | He, Dongxuan1,2,3,4; Zhang, Wei2,3,5; Deng, Hongzhang1,4; Huo, Shuaidong2,3,5; Wang, Yi-Feng2,3,5; Gong, Ningqiang2,3,5; Deng, Liandong1,4; Liang, Xing-Jie2,3,5; Dong, Anjie1,4 |
| 刊名 | Chemical communications
 |
| 出版日期 | 2016 |
| 卷号 | 52期号:98页码:14145-14148 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c6cc07595a |
| 通讯作者 | Liang, xing-jie(liangxj@nanoctr.cn) ; Dong, anjie(ajdong@tju.edu.cn) |
| 英文摘要 | A novel amphiphilic camptothecin prodrug, cpt-ss-ir, consisting of cpt, ir and a disulfide bond linker, was synthesized, and it could self-assemble into nanowires in aqueous solution. upon intracellular triggering, active cpt and ir species were released to exert a considerable anticancer effect. |
| WOS关键词 | ANTITUMOR-ACTIVITY ; ANTICANCER DRUGS ; TOPOISOMERASE-I ; CANCER-THERAPY ; DELIVERY ; AGENTS ; NANOSTRUCTURES ; NANOCAPSULES ; ANALOGS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000390437900017 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176612 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Liang, Xing-Jie; Dong, Anjie |
| 作者单位 | 1.Tianjin Univ, Dept Polymer Sci & Technol, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China 2.Chinese Acad Sci, Lab Controllable Nanopharmaceut, Ctr Excellence Nanosci, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 3.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 4.Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Dongxuan,Zhang, Wei,Deng, Hongzhang,et al. Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation[J]. Chemical communications,2016,52(98):14145-14148. |
| APA | He, Dongxuan.,Zhang, Wei.,Deng, Hongzhang.,Huo, Shuaidong.,Wang, Yi-Feng.,...&Dong, Anjie.(2016).Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation.Chemical communications,52(98),14145-14148. |
| MLA | He, Dongxuan,et al."Self-assembling nanowires of an amphiphilic camptothecin prodrug derived from homologous derivative conjugation".Chemical communications 52.98(2016):14145-14148. |
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