Size-dependent effect of prochloraz-loaded mpeg-plga micro- and nanoparticles
文献类型：期刊论文
| 作者 | Zhang, Jiakun1,2; Zhao, Caiyan2; Liu, Yajing1; Cao, Lidong1; Wu, Yan2; Huang, Qiliang1 |
| 刊名 | Journal of nanoscience and nanotechnology
 |
| 出版日期 | 2016-06-01 |
| 卷号 | 16期号:6页码:6231-6237 |
| 关键词 | Prochloraz Pesticide Mpeg-plga Sustained release Size-dependent effect Fusarium graminearum |
| ISSN号 | 1533-4880 |
| DOI | 10.1166/jnn.2016.10894 |
| 通讯作者 | Wu, yan() ; Huang, qiliang() |
| 英文摘要 | As a controlled release formulation, polymer-based pesticide particle, provide an effective approach to achieve the target crop sites of increasing the pesticide utilization and reducing side effects. the particle size impacts on the dispersibility, pesticide loading content, control effect, etc. it is essential to investigate size-dependent effect. hence, size-dependent effect of polymer-based pesticide particle was studied systematically in this paper. the biodegradable mpeg-plga copolymer with suitable molecular weight (45 kda) was selected as carrier. prochloraz-loaded mpeg-plga particles with different sizes (190.7 nm, 708.8 nm and 3980.0 nm) were constructed by emulsion/solvent evaporation method based on the same carrier. with the constant mass ratio of copolymer/prochloraz, as the particle size became large, the prochloraz loading content increased, and prochloraz released speed decreased. all prochloraz-loaded particles showed a sustained-release process and sustained impact against the fusarium graminearum. among the prochloraz-loaded mpeg-plga particles, the 190.7 nm particles exhibited the best germicidal efficacy in two weeks. hence, the smaller size particles hold a better control efficacy in short time. |
| WOS关键词 | SOLVENT EVAPORATION TECHNIQUE ; COPOLYMER NANOPARTICLES ; CONTROLLED-RELEASE ; POLY(ETHYLENE GLYCOL) ; SILICA NANOPARTICLES ; GOLD NANOPARTICLES ; BLOCK-COPOLYMERS ; IN-VITRO ; DELIVERY ; MICROCAPSULES |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 语种 | 英语 |
| WOS记录号 | WOS:000386123900115 |
| 出版者 | AMER SCIENTIFIC PUBLISHERS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176648 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Wu, Yan; Huang, Qiliang |
| 作者单位 | 1.CAAS, Inst Plant Protect, MOA, Key Lab Pesticide Chem & Applicat, 2 Yuanmingyuan West Rd, Beijing 100193, Peoples R China 2.Natl Ctr Nanosci & Technol, CAS Key Lab Biomed Effects Nanomat & Nanosafety, 11 Beiyitiao, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jiakun,Zhao, Caiyan,Liu, Yajing,et al. Size-dependent effect of prochloraz-loaded mpeg-plga micro- and nanoparticles[J]. Journal of nanoscience and nanotechnology,2016,16(6):6231-6237. |
| APA | Zhang, Jiakun,Zhao, Caiyan,Liu, Yajing,Cao, Lidong,Wu, Yan,&Huang, Qiliang.(2016).Size-dependent effect of prochloraz-loaded mpeg-plga micro- and nanoparticles.Journal of nanoscience and nanotechnology,16(6),6231-6237. |
| MLA | Zhang, Jiakun,et al."Size-dependent effect of prochloraz-loaded mpeg-plga micro- and nanoparticles".Journal of nanoscience and nanotechnology 16.6(2016):6231-6237. |
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来源：高能物理研究所
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