Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers
文献类型：期刊论文
| 作者 | Qiao, Yadong1; Yao, Zhiyi2; Ge, Wenqi2; Zhang, Li1; Wu, Hai-Chen2 |
| 刊名 | Organic & biomolecular chemistry
 |
| 出版日期 | 2017-03-28 |
| 卷号 | 15期号:12页码:2569-2574 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c7ob00115k |
| 通讯作者 | Yao, zhiyi(yaozy@ihep.ac.cn) ; Zhang, li(lizhang9@zzu.edu.cn) ; Wu, hai-chen(haichenwu@ihep.ac.cn) |
| 英文摘要 | We have developed a ratiometric sensor based on polyelectrolyte- induced pyrene excimers for the rapid and visual detection of heparin in aqueous media. this sensor has a simple preparation method, fast response, low cost, and high sensitivity and selectivity. as a complementary strategy for the detection of heparin based on the formation of pyrene excimers, this approach could identify heparin specifically over chondroitin sulphate, which is the major interferent in most sensing systems for the detection of heparin. the detection limit of this approach can be as low as 0.14 mu m using fluorescence measurements. to the best of our knowledge, this is among the lowest lod for the detection of heparin reported in the literature. it enables the rapid and visual detection of heparin both in buffered solution and serum samples. |
| WOS关键词 | ELECTROCHEMICAL SENSOR ; NANOPARTICLES ; PROTAMINE ; ASSAY |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000397948000013 |
| 出版者 | ROYAL SOC CHEMISTRY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176689 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Yao, Zhiyi; Zhang, Li; Wu, Hai-Chen |
| 作者单位 | 1.Zhengzhou Univ, Sch Mat Sci & Engn, Zhengzhou 450052, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiao, Yadong,Yao, Zhiyi,Ge, Wenqi,et al. Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers[J]. Organic & biomolecular chemistry,2017,15(12):2569-2574. |
| APA | Qiao, Yadong,Yao, Zhiyi,Ge, Wenqi,Zhang, Li,&Wu, Hai-Chen.(2017).Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers.Organic & biomolecular chemistry,15(12),2569-2574. |
| MLA | Qiao, Yadong,et al."Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers".Organic & biomolecular chemistry 15.12(2017):2569-2574. |
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来源：高能物理研究所
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