An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo
文献类型：期刊论文
| 作者 | Sun, Wen1; Li, Shuyi2,3; Haupler, Bernhard4; Liu, Juan2,3; Jin, Shubin2,3; Steffen, Werner1; Schubert, Ulrich S.4; Butt, Hans-Jugen1; Liang, Xing-Jie2,3; Wu, Si1 |
| 刊名 | Advanced materials
 |
| 出版日期 | 2017-02-10 |
| 卷号 | 29期号:6页码:6 |
| ISSN号 | 0935-9648 |
| DOI | 10.1002/adma.201603702 |
| 通讯作者 | Liang, xing-jie(liangxj@nanoctr.cn) ; Wu, si(wusi@mpip-mainz.mpg.de) |
| 英文摘要 | An amphiphilic ru-containing block copolymer is used as a photoactivated polymetallodrug for anticancer phototherapy. the block copolymer self-assembles into nanoparticles, which can accumulate at tumor sites in a mouse model. red light irradiation of the block copolymer nanoparticles releases anticancer ru complexes and generates cytotoxic o-1(2), both of which can inhibit tumor growth. |
| WOS关键词 | NEAR-INFRARED LIGHT ; MESOPOROUS SILICA NANOPARTICLES ; DRUG-DELIVERY ; UPCONVERTING NANOPARTICLES ; POLYPYRIDYL COMPLEXES ; ANTICANCER DRUG ; RU(II) COMPLEX ; UP-CONVERSION ; CANCER-CELLS ; SELECTIVITY |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 语种 | 英语 |
| WOS记录号 | WOS:000396143000011 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176809 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Liang, Xing-Jie; Wu, Si |
| 作者单位 | 1.Max Planck Inst Polymer Res, Ackermannweg 10, D-55128 Mainz, Germany 2.Chinese Acad Sci, Ctr Excellence Nanosci, Beijing 100190, Peoples R China 3.Chinese Acad Sci, Natl Ctr Nanosci & Technol, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 4.Friedrich Schiller Univ Jena, Lab Organ & Macromol Chem IOMC, Jena Ctr Soft Matter JCSM, D-07743 Jena, Germany |
| 推荐引用方式 GB/T 7714 | Sun, Wen,Li, Shuyi,Haupler, Bernhard,et al. An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo[J]. Advanced materials,2017,29(6):6. |
| APA | Sun, Wen.,Li, Shuyi.,Haupler, Bernhard.,Liu, Juan.,Jin, Shubin.,...&Wu, Si.(2017).An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo.Advanced materials,29(6),6. |
| MLA | Sun, Wen,et al."An amphiphilic ruthenium polymetallodrug for combined photodynamic therapy and photochemotherapy in vivo".Advanced materials 29.6(2017):6. |
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来源：高能物理研究所
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