Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with alzheimer's disease: a positron emission tomography study
文献类型：期刊论文
| 作者 | Lu, Yang-jia1,2; Cai, Xiao-wen1; Zhang, Gui-feng3; Huang, Yong1; Tang, Chun-zhi4; Shan, Bao-ci5; Cui, Shao-yang4,6; Chen, Jun-qi7; Qu, Shan-shan; Zhong, Zheng1 |
| 刊名 | Neural regeneration research
 |
| 出版日期 | 2017-07-01 |
| 卷号 | 12期号:7页码:1159-1165 |
| 关键词 | Nerve regeneration Neurodegeneration Acupuncture Zusanli (st36) Alzheimer's disease Long-term treatment Positron emission tomography Rat Mechanism Targeting effect Compensation Multi-target regulation Neural regeneration |
| ISSN号 | 1673-5374 |
| DOI | 10.4103/1673-5374.211197 |
| 通讯作者 | Huang, yong(nanfanglihuang@163.com) ; Tang, chun-zhi(jordan664@163.com) |
| 英文摘要 | The acute effect of acupuncture on alzheimer's disease, i.e., on brain activation during treatment, has been reported. however, the effect of long-term acupuncture on brain activation in alzheimer's disease is unclear. therefore, in this study, we performed long-term needling at zusanli (st36) or a sham point (1.5 mm lateral to st36) in a rat alzheimer's disease model, for 30 minutes, once per day, for 30 days. the rats underwent 1 f-fluorodeoxyglucose positron emission tomography scanning. positron emission tomography images were processed with spm2. the brain areas activated after needling at st36 included the left hippocampus, the left orbital cortex, the left infralimbic cortex, the left olfactory cortex, the left cerebellum and the left pons. in the sham-point group, the activated regions were similar to those in the st36 group. however, the st36 group showed greater activation in the cerebellum and pons than the sham-point group. these findings suggest that long-term acupuncture treatment has targeted regulatory effects on multiple brain regions in rats with alzheimer's disease. |
| WOS关键词 | METABOLISM |
| WOS研究方向 | Cell Biology ; Neurosciences & Neurology |
| WOS类目 | Cell Biology ; Neurosciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000407199500026 |
| 出版者 | MEDKNOW PUBLICATIONS & MEDIA PVT LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2176989 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Huang, Yong; Tang, Chun-zhi |
| 作者单位 | 1.Southern Med Univ, Sch Tradit Chinese Med, Guangzhou, Guangdong, Peoples R China 2.Guangdong Med Coll, Clin Sch 2, Tradit Chinese Med, Dongguan, Guangdong, Peoples R China 3.Zhaoqing Med Coll, Zhaoqing, Guangdong, Peoples R China 4.Guangzhou Univ Chinese Med, Clin Med Coll Acupuncture Moxibust & Rehabil, Guangzhou, Guangdong, Peoples R China 5.Chinese Acad Sci, Inst High Energy Phys, Key Lab Nucl Analyt Tech, Beijing, Peoples R China 6.Guangzhou Univ Chinese Med, Shenzhen Hosp, Shenzhen, Guangdong, Peoples R China 7.Southern Med Univ, Huarui Hosp, Guangzhou, Guangdong, Peoples R China 8.Univ Western Sydney, Natl Inst Complementary Med, Penrith, NSW, Australia |
| 推荐引用方式 GB/T 7714 | Lu, Yang-jia,Cai, Xiao-wen,Zhang, Gui-feng,et al. Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with alzheimer's disease: a positron emission tomography study[J]. Neural regeneration research,2017,12(7):1159-1165. |
| APA | Lu, Yang-jia.,Cai, Xiao-wen.,Zhang, Gui-feng.,Huang, Yong.,Tang, Chun-zhi.,...&Steiner, Genevieve Zara.(2017).Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with alzheimer's disease: a positron emission tomography study.Neural regeneration research,12(7),1159-1165. |
| MLA | Lu, Yang-jia,et al."Long-term acupuncture treatment has a multi-targeting regulation on multiple brain regions in rats with alzheimer's disease: a positron emission tomography study".Neural regeneration research 12.7(2017):1159-1165. |
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来源：高能物理研究所
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