The application of stimuli-responsive nanocarriers for targeted drug delivery
文献类型：期刊论文
| 作者 | Zhou, Mengxue; Wen, Kaikai; Bi, Ying; Lu, Huiru; Chen, Jun; Hu, Yi; Chai, Zhifang |
| 刊名 | Current topics in medicinal chemistry
 |
| 出版日期 | 2017 |
| 卷号 | 17期号:20页码:2319-2334 |
| 关键词 | Stimuli-response Nanoparticles Drug delivery Tumor microenvironment Chemotherapy |
| ISSN号 | 1568-0266 |
| DOI | 10.2174/1568026617666170224121008 |
| 通讯作者 | Chen, jun(chenjun@ihep.ac.cn) |
| 英文摘要 | Nanocarriers are widely used for delivering drugs to tumors and are progressing in a stable trend, because malignant tumors remain a major health burden throughout the world and effective therapeutic strategies are urgently needed. furthermore, as an integrated platform, nanocarriers have the potential to dramatically improve cancer diagnosis, imaging, and therapy, while reducing the toxicity associated with the current approaches. significantly, intelligent nanocarriers are the new generation of the nanocarriers, exhibiting superior tumor targeting and improved therapeutic efficacy. in this review, we discuss recent development in the design of nanoscale stimuli-responsive systems which will be able to control drug biodistribution in response to specific stimuli, either exogenous or endogenous. meanwhile, the recent progress in engineering intelligent and versatile nanomaterials for targeting the tumor microenvironment is summarized. |
| WOS关键词 | MESOPOROUS SILICA NANOPARTICLES ; NEAR-INFRARED LIGHT ; BLOCK-COPOLYMER MICELLES ; ENHANCED INTRACELLULAR DELIVERY ; GENERATING LIPOSOMAL SYSTEM ; CELL-PENETRATING PEPTIDES ; IRON-OXIDE NANOPARTICLES ; TUMOR XENOGRAFT MODEL ; GENE DELIVERY ; CANCER-THERAPY |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Chemistry, Medicinal |
| 语种 | 英语 |
| WOS记录号 | WOS:000405625600007 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177248 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Chen, Jun |
| 作者单位 | Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Multidisciplinary Res Div, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Mengxue,Wen, Kaikai,Bi, Ying,et al. The application of stimuli-responsive nanocarriers for targeted drug delivery[J]. Current topics in medicinal chemistry,2017,17(20):2319-2334. |
| APA | Zhou, Mengxue.,Wen, Kaikai.,Bi, Ying.,Lu, Huiru.,Chen, Jun.,...&Chai, Zhifang.(2017).The application of stimuli-responsive nanocarriers for targeted drug delivery.Current topics in medicinal chemistry,17(20),2319-2334. |
| MLA | Zhou, Mengxue,et al."The application of stimuli-responsive nanocarriers for targeted drug delivery".Current topics in medicinal chemistry 17.20(2017):2319-2334. |
入库方式： iSwitch采集
来源：高能物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。