Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract
文献类型：期刊论文
| 作者 | Zu, Yan; Yong, Yuan; Zhang, Xiao; Yu, Jie; Dong, Xinghua; Yin, Wenyan; Yan, Liang; Zhao, Feng; Gu, Zhanjun; Zhao, Yuliang |
| 刊名 | Rsc advances
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:28页码:17505-17513 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c7ra01526g |
| 通讯作者 | Yan, liang() |
| 英文摘要 | Non-invasive imaging modalities such as computed tomography are often used for diagnosis and assessment of gastrointestinal (gi) disease status over the long-term. the physiology of the gi tract can be assessed with contrast agents. here, we present common protein (bovine serum albumin, bsa) stabilized bismuth sulfide nanoparticles with robust x-ray attenuation. under the optimal conditions, this agent can outline the anatomy of the mouse gi tract on 3d computed tomography imaging, with the real-time and non-invasive visualization of nanoparticle distribution and the gi tract. moreover, the investigation on long-term toxicity and biodistribution of these nanoparticles after oral administration indicate their overall safety. this is a promising agent for gi visualization and disease diagnosis. |
| WOS关键词 | BISMUTH SULFIDE NANOPARTICLES ; LARGE-SCALE SYNTHESIS ; COMPUTED-TOMOGRAPHY ; IN-VIVO ; ASSISTED SYNTHESIS ; NANODOTS ; NANORODS ; CANCER ; DELIVERY ; THERAPY |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000398802000068 |
| 出版者 | ROYAL SOC CHEMISTRY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177462 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Yan, Liang |
| 作者单位 | Chinese Acad Sci, Inst High Energy Phys, Natl Ctr Nanosci Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zu, Yan,Yong, Yuan,Zhang, Xiao,et al. Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract[J]. Rsc advances,2017,7(28):17505-17513. |
| APA | Zu, Yan.,Yong, Yuan.,Zhang, Xiao.,Yu, Jie.,Dong, Xinghua.,...&Zhao, Yuliang.(2017).Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract.Rsc advances,7(28),17505-17513. |
| MLA | Zu, Yan,et al."Protein-directed synthesis of bi2s3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract".Rsc advances 7.28(2017):17505-17513. |
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来源：高能物理研究所
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