中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Preparation of green and gelatin-free nanocrystalline cellulose capsules

文献类型:期刊论文

作者Zhang, Yapei1,2,5; Zhao, Qing3; Wang, Huashan4; Jiang, Xingyu1,2; Cha, Ruitao1,2
刊名Carbohydrate polymers
出版日期2017-05-15
卷号164页码:358-363
关键词Nanocrystalline cellulose Capsule Rheology Swelling Disintegration
ISSN号0144-8617
DOI10.1016/j.carbpol.2017.01.096
通讯作者Jiang, xingyu(xingyujiang@nanoctr.cn) ; Cha, ruitao(chart@nanoctr.cn)
英文摘要The ambiguous source and uncontrolled solubility of gelatin make it crucial to develop gelatin capsule substitutes. nanocrystalline cellulose (ncc) of excellent mechanical performance, good biocompatibility and green origin has drawn many attentions as a new class of biomaterials. in this work, ncc capsule was prepared by dipping method with peg and glycerol as plasticizer. the effect of peg and glycerol on the rheological property of ncc gel and the surface morphology of ncc capsule was evaluated. the disintegration time of ncc capsule meet the criteria in united states pharmacopoeia (usp32-701). there is no significant difference in the release of sulfuric acid between gelatin capsule and ncc capsule. ncc capsule thus has the potential as a green platform for biomedical applications in drug delivery. (c) 2017 elsevier ltd. all rights reserved.
WOS关键词MECHANICAL-PROPERTIES ; EDIBLE FILMS ; CROSS-LINKING ; COMPOSITES ; PERMEABILITY ; POLYETHYLENE ; THICKNESS ; AGENT ; PAPER
WOS研究方向Chemistry ; Polymer Science
WOS类目Chemistry, Applied ; Chemistry, Organic ; Polymer Science
语种英语
WOS记录号WOS:000398759400041
出版者ELSEVIER SCI LTD
URI标识http://www.irgrid.ac.cn/handle/1471x/2177465
专题高能物理研究所
通讯作者Jiang, Xingyu; Cha, Ruitao
作者单位1.Chinese Acad Sci, Ctr Excellence Nanosci, Natl Ctr NanoSci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Ctr Excellence Nanosci, Natl Ctr NanoSci & Technol, Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
3.Tianjin Entry Exit Inspect & Quarantine Bur PR Ch, Tianjin 300042, Peoples R China
4.Tianjin Univ Sci & Technol, Sch Chem Engn & Mat Sci, Tianjin 300457, Peoples R China
5.Nankai Univ, Inst Polymer Chem, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Yapei,Zhao, Qing,Wang, Huashan,et al. Preparation of green and gelatin-free nanocrystalline cellulose capsules[J]. Carbohydrate polymers,2017,164:358-363.
APA Zhang, Yapei,Zhao, Qing,Wang, Huashan,Jiang, Xingyu,&Cha, Ruitao.(2017).Preparation of green and gelatin-free nanocrystalline cellulose capsules.Carbohydrate polymers,164,358-363.
MLA Zhang, Yapei,et al."Preparation of green and gelatin-free nanocrystalline cellulose capsules".Carbohydrate polymers 164(2017):358-363.

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来源:高能物理研究所

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