Preparation of green and gelatin-free nanocrystalline cellulose capsules
文献类型:期刊论文
作者 | Zhang, Yapei1,2,5; Zhao, Qing3; Wang, Huashan4; Jiang, Xingyu1,2; Cha, Ruitao1,2 |
刊名 | Carbohydrate polymers
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出版日期 | 2017-05-15 |
卷号 | 164页码:358-363 |
关键词 | Nanocrystalline cellulose Capsule Rheology Swelling Disintegration |
ISSN号 | 0144-8617 |
DOI | 10.1016/j.carbpol.2017.01.096 |
通讯作者 | Jiang, xingyu(xingyujiang@nanoctr.cn) ; Cha, ruitao(chart@nanoctr.cn) |
英文摘要 | The ambiguous source and uncontrolled solubility of gelatin make it crucial to develop gelatin capsule substitutes. nanocrystalline cellulose (ncc) of excellent mechanical performance, good biocompatibility and green origin has drawn many attentions as a new class of biomaterials. in this work, ncc capsule was prepared by dipping method with peg and glycerol as plasticizer. the effect of peg and glycerol on the rheological property of ncc gel and the surface morphology of ncc capsule was evaluated. the disintegration time of ncc capsule meet the criteria in united states pharmacopoeia (usp32-701). there is no significant difference in the release of sulfuric acid between gelatin capsule and ncc capsule. ncc capsule thus has the potential as a green platform for biomedical applications in drug delivery. (c) 2017 elsevier ltd. all rights reserved. |
WOS关键词 | MECHANICAL-PROPERTIES ; EDIBLE FILMS ; CROSS-LINKING ; COMPOSITES ; PERMEABILITY ; POLYETHYLENE ; THICKNESS ; AGENT ; PAPER |
WOS研究方向 | Chemistry ; Polymer Science |
WOS类目 | Chemistry, Applied ; Chemistry, Organic ; Polymer Science |
语种 | 英语 |
WOS记录号 | WOS:000398759400041 |
出版者 | ELSEVIER SCI LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177465 |
专题 | 高能物理研究所 |
通讯作者 | Jiang, Xingyu; Cha, Ruitao |
作者单位 | 1.Chinese Acad Sci, Ctr Excellence Nanosci, Natl Ctr NanoSci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Ctr Excellence Nanosci, Natl Ctr NanoSci & Technol, Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Tianjin Entry Exit Inspect & Quarantine Bur PR Ch, Tianjin 300042, Peoples R China 4.Tianjin Univ Sci & Technol, Sch Chem Engn & Mat Sci, Tianjin 300457, Peoples R China 5.Nankai Univ, Inst Polymer Chem, Key Lab Funct Polymer Mat, Minist Educ, Tianjin 300071, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Yapei,Zhao, Qing,Wang, Huashan,et al. Preparation of green and gelatin-free nanocrystalline cellulose capsules[J]. Carbohydrate polymers,2017,164:358-363. |
APA | Zhang, Yapei,Zhao, Qing,Wang, Huashan,Jiang, Xingyu,&Cha, Ruitao.(2017).Preparation of green and gelatin-free nanocrystalline cellulose capsules.Carbohydrate polymers,164,358-363. |
MLA | Zhang, Yapei,et al."Preparation of green and gelatin-free nanocrystalline cellulose capsules".Carbohydrate polymers 164(2017):358-363. |
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来源:高能物理研究所
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