Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis
文献类型：期刊论文
| 作者 | Barabadi, Hamed1; Alizadeh, Ahad2; Ovais, Muhammad3,4; Ahmadi, Amirhossein5; Shinwari, Zabta Khan3; Saravanan, Muthupandian6 |
| 刊名 | Iet nanobiotechnology
 |
| 出版日期 | 2018-06-01 |
| 卷号 | 12期号:4页码:377-391 |
| ISSN号 | 1751-8741 |
| 关键词 | Reviews Nanoparticles Cancer Nanomedicine Magnetic particles Nanomagnetics Nanofabrication Cellular biophysics Bayes methods Microorganisms Toxicology Antibacterial activity Green nanoparticles Cancerous cell lines Normal cell lines Review Meta-analysis Microbial synthesised metallic nanoparticles Bayesian generalised linear model Hela cancer cell lines A549 cancer cell lines Gram-negative bacteria Gram-positive bacteria Cytotoxicity Anticancer agents Cancer disease treatment |
| DOI | 10.1049/iet-nbt.2017.0120 |
| 通讯作者 | Saravanan, muthupandian(saravanan.muthupandian@mu.edu.et) |
| 英文摘要 | This study aimed to perform a systematic review and meta-analysis of papers discussing the efficacy of microbial synthesised metallic nanoparticles (mnps) against cancerous and normal cell lines by exploiting bayesian generalised linear (bgl) model. data was systematically collected from published papers via cochrane library, web of science, pubmed, science direct, proquest, scopus, and embase. impressively, most of the studies were carried out on hela and a549 cancer cell lines. specifically, a hefty 65.67% of studies employed bacteria to biofabricate mnps. significantly, bgl meta-analysis represented highly valuable information. hence, based on adjusted analysis, the mnps with the size of 25-50 nm were found to be far less cytotoxic than the mnps with the size of <= 25 nm (or=0.233, p<0.05) against either cancerous or normal cell lines. interestingly, it was found that the odds of cytotoxicity in cancerous cell lines were practically nine times more than normal cell lines, representing the substantially more cytotoxicity of mnps in cancerous cell lines (or=9.004, p<0.001). green mnps mentioned here may be developed as novel anti-cancer agents, which could lead to a revolution in the treatment of cancer. |
| WOS关键词 | BIOSYNTHESIZED SILVER NANOPARTICLES ; NOBLE-METAL NANOPARTICLES ; GOLD NANOPARTICLES ; EXTRACELLULAR BIOSYNTHESIS ; SELENIUM NANOPARTICLES ; OXIDE NANOPARTICLES ; ANTICANCER ACTIVITY ; MEDIATED SYNTHESIS ; INORGANIC NANOPARTICLES ; ECHINOCOCCUS-GRANULOSUS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Science & Technology - Other Topics |
| WOS类目 | Biochemical Research Methods ; Nanoscience & Nanotechnology |
| 语种 | 英语 |
| 出版者 | INST ENGINEERING TECHNOLOGY-IET |
| WOS记录号 | WOS:000432264100001 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177513 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Saravanan, Muthupandian |
| 作者单位 | 1.Shahid Beheshti Univ Med Sci, Sch Pharm, Dept Pharmaceut Biotechnol, Tehran, Iran 2.ACECR, Royan Inst Reprod Biomed, Reprod Epidemiol Res Ctr, Dept Epidemiol & Reprod Hlth, Tehran, Iran 3.Quaid I Azam Univ, Fac Biol Sci, Dept Biotechnol, Islamabad 45320, Pakistan 4.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 5.Mazandaran Univ Med Sci, Fac Pharm, Pharmaceut Sci Res Ctr, Sari, Iran 6.Mekelle Univ, Coll Hlth Sci, Inst Biomed Sci, Dept Med Microbiol & Immunol, Mekelle 1871, Ethiopia |
| 推荐引用方式 GB/T 7714 | Barabadi, Hamed,Alizadeh, Ahad,Ovais, Muhammad,et al. Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis[J]. Iet nanobiotechnology,2018,12(4):377-391. |
| APA | Barabadi, Hamed,Alizadeh, Ahad,Ovais, Muhammad,Ahmadi, Amirhossein,Shinwari, Zabta Khan,&Saravanan, Muthupandian.(2018).Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis.Iet nanobiotechnology,12(4),377-391. |
| MLA | Barabadi, Hamed,et al."Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis".Iet nanobiotechnology 12.4(2018):377-391. |
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