Self-assembled peptide-based nanomaterials for biomedical imaging and therapy
文献类型：期刊论文
| 作者 | Qi, Guo-Bin; Gao, Yu-Juan; Wang, Lei; Wang, Hao |
| 刊名 | Advanced materials
 |
| 出版日期 | 2018-05-29 |
| 卷号 | 30期号:22页码:34 |
| ISSN号 | 0935-9648 |
| 关键词 | Bioimaging Drug delivery Nanomaterials Peptides Self-assembly |
| DOI | 10.1002/adma.201703444 |
| 通讯作者 | Wang, lei(wanglei@nanoctr.cn) ; Wang, hao(wanghao@nanoctr.cn) |
| 英文摘要 | Peptide-based materials are one of the most important biomaterials, with diverse structures and functionalities. over the past few decades, a self-assembly strategy is introduced to construct peptide-based nanomaterials, which can form well-controlled superstructures with high stability and multivalent effect. more recently, peptide-based functional biomaterials are widely utilized in clinical applications. however, there is no comprehensive review article that summarizes this growing area, from fundamental research to clinic translation. in this review, the recent progress of peptide-based materials, from molecular building block peptides and self-assembly driving forces, to biomedical and clinical applications is systematically summarized. ex situ and in situ constructed nanomaterials based on functional peptides are presented. the advantages of intelligent in situ construction of peptide-based nanomaterials in vivo are emphasized, including construction strategy, nanostructure modulation, and biomedical effects. this review highlights the importance of self-assembled peptide nanostructures for nanomedicine and can facilitate further knowledge and understanding of these nanosystems toward clinical translation. |
| WOS关键词 | AGGREGATION-INDUCED EMISSION ; FDA DRUG APPROVALS ; ENZYME-RESPONSIVE NANOPARTICLES ; RESONANCE ENERGY-TRANSFER ; ELASTIN-LIKE POLYPEPTIDE ; BREAST-CANCER CELLS ; ACTIVITY IN-VIVO ; LIGHT-UP PROBE ; PHAGE DISPLAY ; SMALL MOLECULES |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 语种 | 英语 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| WOS记录号 | WOS:000434034100034 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177534 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Wang, Lei; Wang, Hao |
| 作者单位 | Natl Ctr Nanosci & Technol NCNST, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, 11 Beiyitiao, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qi, Guo-Bin,Gao, Yu-Juan,Wang, Lei,et al. Self-assembled peptide-based nanomaterials for biomedical imaging and therapy[J]. Advanced materials,2018,30(22):34. |
| APA | Qi, Guo-Bin,Gao, Yu-Juan,Wang, Lei,&Wang, Hao.(2018).Self-assembled peptide-based nanomaterials for biomedical imaging and therapy.Advanced materials,30(22),34. |
| MLA | Qi, Guo-Bin,et al."Self-assembled peptide-based nanomaterials for biomedical imaging and therapy".Advanced materials 30.22(2018):34. |
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来源：高能物理研究所
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