中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Specific detection and effective inhibition of a single bacterial species in situ using peptide mineralized au cluster probes

文献类型:期刊论文

作者Zhang, Xiangchun1,3; Liu, Li1; Liu, Ru1; Wang, Jing1; Hu, Xuhu1; Yuan, Qing1; Guo, Juanjuan1; Xing, Gengmei1; Zhao, Yuliang1; Gao, Xueyun1,2
刊名Science china-chemistry
出版日期2018-05-01
卷号61期号:5页码:627-634
关键词Au cluster probes Single bacteria species S. aureus Specific detection Effective inhibition
ISSN号1674-7291
DOI10.1007/s11426-017-9206-y
通讯作者Liu, ru(liuru@ihep.ac.cn) ; Gao, xueyun(gaoxy@ihep.ac.cn)
英文摘要Increasingly serious microbial infections call for the development of new simpler methods for the precise diagnosis and specific inhibition of such pathogens. in this work, a peptide mineralized au cluster probe was applied as a new simplified strategy to both recognize and inhibit a single bacteria species of staphylococcus aureus (s. aureus) simultaneously. the probes are composed of peptides and au clusters. moreover, the peptides specifically target s. aureus cells and the au clusters provide fluorescent imaging and have an antibacterial effect. these new probes enable the simultaneous specific detection and effective destruction s. aureus cells in situ.
WOS关键词ANTIBIOTIC-RESISTANT BACTERIA ; GRAM-POSITIVE BACTERIA ; STAPHYLOCOCCUS-AUREUS ; GOLD NANOCLUSTERS ; ANTIBACTERIAL APPLICATIONS ; ANTIMICROBIAL AGENTS ; INFECTIOUS-DISEASES ; NANOPARTICLES ; CELL ; PATHOGENS
WOS研究方向Chemistry
WOS类目Chemistry, Multidisciplinary
语种英语
WOS记录号WOS:000431179300019
出版者SCIENCE PRESS
URI标识http://www.irgrid.ac.cn/handle/1471x/2177599
专题高能物理研究所
通讯作者Liu, Ru; Gao, Xueyun
作者单位1.Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China
2.Beijing Univ Technol, Dept Chem & Chem Engn, Beijing 100124, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Xiangchun,Liu, Li,Liu, Ru,et al. Specific detection and effective inhibition of a single bacterial species in situ using peptide mineralized au cluster probes[J]. Science china-chemistry,2018,61(5):627-634.
APA Zhang, Xiangchun.,Liu, Li.,Liu, Ru.,Wang, Jing.,Hu, Xuhu.,...&Gao, Xueyun.(2018).Specific detection and effective inhibition of a single bacterial species in situ using peptide mineralized au cluster probes.Science china-chemistry,61(5),627-634.
MLA Zhang, Xiangchun,et al."Specific detection and effective inhibition of a single bacterial species in situ using peptide mineralized au cluster probes".Science china-chemistry 61.5(2018):627-634.

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来源:高能物理研究所

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