Dspe-peg: a distinctive component in drug delivery system
文献类型：期刊论文
| 作者 | Che, Jing1,2; Okeke, Chukwunweike I.1; Hu, Zhong-Bo2; Xu, Jing1 |
| 刊名 | Current pharmaceutical design
 |
| 出版日期 | 2015 |
| 卷号 | 21期号:12页码:1598-1605 |
| 关键词 | Dspe-peg Blood circulation time Biostability Liposomes Micelles Drug delivery |
| ISSN号 | 1381-6128 |
| 通讯作者 | Xu, jing(xujing@nanoctr.cn) |
| 英文摘要 | 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-poly(ethylene glycol) (dspe-peg) is a widely used phospholipids-polymer conjugate in drug delivery applications. it is a biocompatible, biodegradable and amphiphilic material which can also be functionalized with various biomolecules for specific functions. with the emerging interest in use of nanocarriers for therapeutic drug delivery and imaging dspe-peg has become a very useful material for the formulation of these nanocarriers for achieving prolonged blood circulation time, improved stability and enhanced encapsulation efficiency. this review will focus on the relationships between the structure of dspe-peg and its noticeable effects on these nanocarriers' properties, and the recent progress on the development of dspe-peg and its derivatives in delivery systems. |
| WOS关键词 | POLYMER HYBRID NANOPARTICLES ; CALCIUM-PHOSPHATE NANOPARTICLES ; PH-SENSITIVE LIPOSOMES ; SIRNA DELIVERY ; IN-VIVO ; THERMOSENSITIVE LIPOSOMES ; POLY(ETHYLENE GLYCOL) ; PEGYLATED LIPOSOMES ; CELLULAR UPTAKE ; TARGETING DELIVERY |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000350281800009 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177626 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Xu, Jing |
| 作者单位 | 1.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Coll Mat Sci & Optoelect Technol, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Che, Jing,Okeke, Chukwunweike I.,Hu, Zhong-Bo,et al. Dspe-peg: a distinctive component in drug delivery system[J]. Current pharmaceutical design,2015,21(12):1598-1605. |
| APA | Che, Jing,Okeke, Chukwunweike I.,Hu, Zhong-Bo,&Xu, Jing.(2015).Dspe-peg: a distinctive component in drug delivery system.Current pharmaceutical design,21(12),1598-1605. |
| MLA | Che, Jing,et al."Dspe-peg: a distinctive component in drug delivery system".Current pharmaceutical design 21.12(2015):1598-1605. |
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来源：高能物理研究所
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