Periodic microstructures of blood capillaries revealed by synchrotron x-ray multi-resolution microscopic analysis
文献类型：期刊论文
| 作者 | Yao, Shengkun1; Zong, Yunbing2,3; Huang, Xu4; Liu, Yang1,2; Gong, Ningqiang5,6,7; Zhang, Jianhua1,2; Li, Ziqing2; Cao, Feng4; Wang, Xiangcheng3; Liang, Xing-Jie5,6,7 |
| 刊名 | Biomedical optics express
 |
| 出版日期 | 2017-12-01 |
| 卷号 | 8期号:12页码:5825-5833 |
| ISSN号 | 2156-7085 |
| DOI | 10.1364/boe.8.005825 |
| 通讯作者 | Jiang, huaidong(jianghd@shanghaitech.edu.cn) |
| 英文摘要 | Cardiovascular diseases arc closely related to structural blood capillaries lesions. herein, microscopic investigations of mouse blood capillaries were performed at multiple spatial resolution by using synchrotron x-ray in-line phase contrast tomography and scanning transmission x-ray microscopy (stxm). the chemically fixed blood capillaries without any contrast agents were selected. for the first time, a periodic bamboo-shaped structure was observed at nanoscale resolution by stxm, and the three-dimensional tomographic slices at sub-micrometer resolution further confirmed the periodic wave profile of the blood capillaries. then, a periodic microstructural model was suggested based on the microscopic images. by using high-performance imaging techniques, this work provides a better understanding of the relationship between the structure and function of blood capillaries, will be helpful in elucidating the causes of cardiovascular system diseases. (c) 2017 optical society of america under the terms of the osa open access publishing agreement |
| WOS关键词 | COMPUTED-TOMOGRAPHY ; HIGH-RESOLUTION ; ANGIOGENESIS ; NANOPARTICLES ; VASCULATURE ; DISEASE |
| WOS研究方向 | Biochemistry & Molecular Biology ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| WOS类目 | Biochemical Research Methods ; Optics ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| 出版者 | OPTICAL SOC AMER |
| WOS记录号 | WOS:000417583800036 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177802 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Jiang, Huaidong |
| 作者单位 | 1.ShanghaiTech Univ, Sch Phys Sci & Technol, Shanghai 201210, Peoples R China 2.Shandong Univ, State Key Lab Crystal Mat, Jinan 250100, Shandong, Peoples R China 3.Inspur Int Ltd, Dept Data & Business Anal Prod, Jinan 250101, Shandong, Peoples R China 4.Chinese Peoples Liberat Army Gen Hosp, Dept Cardiol, Beijing 100853, Peoples R China 5.Chinese Acad Sci, Lab Controllable Nanopharmaceut, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 6.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, 11 First North Rd Zhongguangcun, Beijing 100190, Peoples R China 7.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yao, Shengkun,Zong, Yunbing,Huang, Xu,et al. Periodic microstructures of blood capillaries revealed by synchrotron x-ray multi-resolution microscopic analysis[J]. Biomedical optics express,2017,8(12):5825-5833. |
| APA | Yao, Shengkun.,Zong, Yunbing.,Huang, Xu.,Liu, Yang.,Gong, Ningqiang.,...&Jiang, Huaidong.(2017).Periodic microstructures of blood capillaries revealed by synchrotron x-ray multi-resolution microscopic analysis.Biomedical optics express,8(12),5825-5833. |
| MLA | Yao, Shengkun,et al."Periodic microstructures of blood capillaries revealed by synchrotron x-ray multi-resolution microscopic analysis".Biomedical optics express 8.12(2017):5825-5833. |
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