Nanotechnology-based strategies for treatment of ocular disease
文献类型：期刊论文
| 作者 | Weng, Yuhua1,2,3; Liu, Juan2,3; Jin, Shubin2,3; Guo, Weisheng2,3; Liang, Xingjie2,3; Hua, Zhongbo1 |
| 刊名 | Acta pharmaceutica sinica b
 |
| 出版日期 | 2017-05-01 |
| 卷号 | 7期号:3页码:281-291 |
| 关键词 | Nanosystems Nanocarrier Eye Ocular disease Ocular drug delivery Therapy Diagnosis |
| ISSN号 | 2211-3835 |
| DOI | 10.1016/j.apsh.2016.09.001 |
| 通讯作者 | Guo, weisheng(guows@nanoctr.cn) ; Liang, xingjie(liangxj@nanoctr.cn) ; Hua, zhongbo(huzq@ucas.ac.cn) |
| 英文摘要 | Ocular diseases include various anterior and posterior segment diseases. due to the unique anatomy and physiology of the eye, efficient ocular drug delivery is a great challenge to researchers and pharmacologists. although there are conventional noninvasive and invasive treatments, such as eye drops, injections and implants, the current treatments either suffer from low bioavailability or severe adverse ocular effects. alternatively, the emerging nanoscience and nanotechnology are playing an important role in the development of novel strategies for ocular disease therapy. various active molecules have been designed to associate with nanocarriers to overcome ocular barriers and intimately interact with specific ocular tissues. in this review, we highlight the recent attempts of nanotechnology-based systems for imaging and treating ocular diseases, such as corneal diseases, glaucoma, retina diseases, and choroid diseases. although additional work remains, the progress described herein may pave the way to new, highly effective and important ocular nanomedicines. (c) 2017 chinese pharmaceutical association and institute of materia medica, chinese academy of medical sciences. production and hosting by elsevier b.v. this is an open access article under the cc by-nc-nd license |
| WOS关键词 | PIGMENT EPITHELIAL-CELLS ; GANCICLOVIR OPHTHALMIC GEL ; LOADED BIODEGRADABLE NANOPARTICLES ; OPTICAL COHERENCE TOMOGRAPHY ; HUMAN RETINOBLASTOMA CELLS ; DRUG-DELIVERY ; IN-VIVO ; PHOTODYNAMIC THERAPY ; SIRNA DELIVERY ; CORNEAL |
| WOS研究方向 | Pharmacology & Pharmacy |
| WOS类目 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000417187900003 |
| 出版者 | INST MATERIA MEDICA, CHINESE ACAD MEDICAL SCIENCES |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177808 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Guo, Weisheng; Liang, Xingjie; Hua, Zhongbo |
| 作者单位 | 1.Univ Chinese Acad Sci, Coll Mat Sci & Optoelect, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Ctr Excellence Nanosci, Lab Controllable Nanopharm, Beijing 100190, Peoples R China 3.Natl Ctr Nanosci & Technol China, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Weng, Yuhua,Liu, Juan,Jin, Shubin,et al. Nanotechnology-based strategies for treatment of ocular disease[J]. Acta pharmaceutica sinica b,2017,7(3):281-291. |
| APA | Weng, Yuhua,Liu, Juan,Jin, Shubin,Guo, Weisheng,Liang, Xingjie,&Hua, Zhongbo.(2017).Nanotechnology-based strategies for treatment of ocular disease.Acta pharmaceutica sinica b,7(3),281-291. |
| MLA | Weng, Yuhua,et al."Nanotechnology-based strategies for treatment of ocular disease".Acta pharmaceutica sinica b 7.3(2017):281-291. |
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