Skiving stacked sheets of paper into test paper for rapid and multiplexed assay
文献类型：期刊论文
| 作者 | Yang, Mingzhu1,2; Zhang, Wei1,2; Yang, Junchuan1,2; Hu, Binfeng1,2; Cao, Fengjing1,2; Zheng, Wenshu1,2; Chen, Yiping1,2; Jiang, Xingyu1,2,3 |
| 刊名 | Science advances
 |
| 出版日期 | 2017-12-01 |
| 卷号 | 3期号:12页码:6 |
| ISSN号 | 2375-2548 |
| DOI | 10.1126/sciadv.aao4862 |
| 通讯作者 | Zhang, wei(zhangw@nanoctr.cn) ; Jiang, xingyu(xingyujiang@nanoctr.cn) |
| 英文摘要 | This paper shows that stacked sheets of paper preincubated with different biological reagents and skiving them into uniform test paper sheets allow mass manufacturing of multiplexed immunoassay devices and simultaneous detection of multiplex targets that can be read out by a barcode scanner. the thickness of one sheet of paper can form the width of a module for the barcode; when stacked, these sheets of paper can form a series of barcodes representing the targets, depending on the color contrast provided by a colored precipitate of an immunoassay. the uniform thickness of sheets of paper allows high-quality signal readout. the manufacturing method allows highly efficient fabrication of the materials and substrates for a straightforward assay of targets that range from drugs of abuse to biomarkers of blood-transmitted infections. in addition, as a novel alternative to the conventional point-of-care testing method, the paper-based barcode assay system can provide highly efficient, accurate, and objective diagnoses. |
| WOS关键词 | ANALYTICAL DEVICES ; SIGNAL AMPLIFICATION ; GOLD NANOPARTICLES ; IMMUNOASSAYS ; DIAGNOSTICS ; NANOSTRUCTURES ; FABRICATION ; NANOSENSOR ; BIOASSAYS ; READOUT |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000418003100029 |
| 出版者 | AMER ASSOC ADVANCEMENT SCIENCE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177831 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Zhang, Wei; Jiang, Xingyu |
| 作者单位 | 1.Natl Ctr Nanosci & Technol, Beijing Engn Res Ctr BioNanotechnol, Beijing 100190, Peoples R China 2.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Mingzhu,Zhang, Wei,Yang, Junchuan,et al. Skiving stacked sheets of paper into test paper for rapid and multiplexed assay[J]. Science advances,2017,3(12):6. |
| APA | Yang, Mingzhu.,Zhang, Wei.,Yang, Junchuan.,Hu, Binfeng.,Cao, Fengjing.,...&Jiang, Xingyu.(2017).Skiving stacked sheets of paper into test paper for rapid and multiplexed assay.Science advances,3(12),6. |
| MLA | Yang, Mingzhu,et al."Skiving stacked sheets of paper into test paper for rapid and multiplexed assay".Science advances 3.12(2017):6. |
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来源：高能物理研究所
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