Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion
文献类型：期刊论文
| 作者 | Chen, Yiping1,2; Yin, Binfeng1,2; Dong, Mingling1,2; Xianyu, Yunlei1,2; Jiang, Xingyu1,2,3 |
| 刊名 | Analytical chemistry
 |
| 出版日期 | 2018-01-16 |
| 卷号 | 90期号:2页码:1234-1240 |
| ISSN号 | 0003-2700 |
| DOI | 10.1021/acs.analchem.7b03961 |
| 通讯作者 | Jiang, xingyu(xingyujiang@nanoctr.cn) |
| 英文摘要 | We report a versatile analytical platform for assaying multiple analytes relying on changes in longitudinal relaxation time (t-1) as a result of fe3+/fe2+ interconversion. the t-1 of water protons in fe3+ aqueous solution differs significantly from that of fe2+, allowing for the development of a generally applicable trbased assay since many redox reactions enable the interconversion between fe' and fe3+ that can result in the change of ti. compared with conventional magnetic biosensors, this t-1-based assay is free of magnetic nanoparticles (mnps), and the stability of t-1 based assay is better than conventional magnetic sensors that suffer from nonspecific adsorption and aggregation of mnps. this t-1-based assay simultaneously enables "one-step mixing" assays (such as saliva sugar) and "multiple-washing" immunoassays with good stability and sensitivity, offering a promising platform for convenient, stable, and versatile biomedical analysis |
| WOS关键词 | MAGNETIC-RESONANCE ; ULTRASENSITIVE DETECTION ; ONE-STEP ; NANOPARTICLES ; RELAXATION ; SEPARATION ; PATHOGENS ; PARTICLES ; CHEMISTRY ; PROTEINS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000423011600029 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177889 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Jiang, Xingyu |
| 作者单位 | 1.Beijing Engn Res Ctr BioNanotechnol, 11 Beiyitiao, Beijing 100190, Peoples R China 2.Natl Ctr NanoSci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biol Effects Nanomat & Nanosafety, 11 Beiyitiao, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, 19 A YuQuan Rd, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Yiping,Yin, Binfeng,Dong, Mingling,et al. Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion[J]. Analytical chemistry,2018,90(2):1234-1240. |
| APA | Chen, Yiping,Yin, Binfeng,Dong, Mingling,Xianyu, Yunlei,&Jiang, Xingyu.(2018).Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion.Analytical chemistry,90(2),1234-1240. |
| MLA | Chen, Yiping,et al."Versatile t-1-based chemical analysis platform using fe3+/fe2+ interconversion".Analytical chemistry 90.2(2018):1234-1240. |
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来源：高能物理研究所
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