Peroxidase-like activity of mos2 nanoflakes with different modifications and their application for h2o2 and glucose detection
文献类型：期刊论文
| 作者 | Yu, Jie1,2; Ma, Dongqing2; Mei, Linqiang2; Gao, Qin2; Yin, Wenyan2; Zhang, Xiao2; Yan, Liang2; Gu, Zhanjun2; Ma, Xiaoyan1; Zhao, Yuliang2 |
| 刊名 | Journal of materials chemistry b
 |
| 出版日期 | 2018-01-21 |
| 卷号 | 6期号:3页码:487-498 |
| ISSN号 | 2050-750X |
| DOI | 10.1039/c7tb02676e |
| 通讯作者 | Yin, wenyan(yinwy@ihep.ac.cn) ; Gu, zhanjun(zjgu@ihep.ac.cn) ; Ma, xiaoyan(m_xiao_yana@nwpu.edu.cn) |
| 英文摘要 | Mos2 nanoflakes (mos2 nfs) with a diameter of b390 nm were obtained by a facile one-pot hydrothermal method and the nfs exhibited intrinsic peroxidase-like activity. after being modified by commonly used biocompatible surfactants including polyethyleneimine (pei), polyacrylic acid (paa), polyvinylpyrrolidone (pvp), and cysteine (cys), the peroxidase-like catalytic activities of mos2 nfs were investigated by using 3,30,5,50-tetramethylbenzidine (tmb) and 2,20-azino-bis(3-ethylbenzothiazoline-6sulfonic acid) diammonium salt (abts) as chromogenic substrates. compared to the polymer modified mos2 nfs, cys functionalized mos2 nfs exhibited a high catalytic activity toward h2o2 in the presence of tmb or abts. zeta potential and michaelis-menten analyses implied that the electrostatic force induced affinity or repulsion between the mos2 nfs and substrates, as well as surface modifications of the mos2 nfs played a key role in the catalytic reactions. notably, a new peroxidase-like catalytic reaction mechanism was proposed based on the formation of a transient state of cys-mos2 nfs containing h2o2 and abts, and the catalytic reaction could occur because the cys on the surface of the mos2 nfs served as an electron transfer bridge between h2o2 and abts. based on this finding, we also established a platform for colorimetric detection of h2o2 and glucose using cys-mos2 nfs as a peroxidase substitution. the limit of detection (lod) was determined to be 4.103 mmol l-1 for h2o2, and the linear range (lr) was from 0 to 0.3 mmol l-1. the lod for glucose was 33.51 mmol l-1 and the lr was from 0.05 to 1 mmol l-1, which is suitable for biomedical diagnosis. this work provides a new insight into the catalytic mechanism of peroxidase-like mos2 nfs, and paves the way for enzyme-like nanomaterials to be used for medical diagnosis. |
| WOS关键词 | MOLYBDENUM-DISULFIDE ; GOLD NANOPARTICLES ; CATALYTIC-ACTIVITY ; ELECTROCHEMICAL DETECTION ; COLORIMETRIC DETECTION ; IRIDIUM NANOPARTICLES ; SYNERGISTIC CATALYST ; PHOTOTHERMAL THERAPY ; HYDROGEN-PEROXIDE ; POLYACRYLIC-ACID |
| WOS研究方向 | Materials Science |
| WOS类目 | Materials Science, Biomaterials |
| 语种 | 英语 |
| WOS记录号 | WOS:000422871100014 |
| 出版者 | ROYAL SOC CHEMISTRY |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177908 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Yin, Wenyan; Gu, Zhanjun; Ma, Xiaoyan |
| 作者单位 | 1.Northwestern Polytech Univ, Sch Sci, Key Lab Polymer Sci & Technol, Xian 710129, Shaanxi, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Jie,Ma, Dongqing,Mei, Linqiang,et al. Peroxidase-like activity of mos2 nanoflakes with different modifications and their application for h2o2 and glucose detection[J]. Journal of materials chemistry b,2018,6(3):487-498. |
| APA | Yu, Jie.,Ma, Dongqing.,Mei, Linqiang.,Gao, Qin.,Yin, Wenyan.,...&Zhao, Yuliang.(2018).Peroxidase-like activity of mos2 nanoflakes with different modifications and their application for h2o2 and glucose detection.Journal of materials chemistry b,6(3),487-498. |
| MLA | Yu, Jie,et al."Peroxidase-like activity of mos2 nanoflakes with different modifications and their application for h2o2 and glucose detection".Journal of materials chemistry b 6.3(2018):487-498. |
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