Application of multifunctional nanomaterials in tumor radiosensitization
文献类型：期刊论文
| 作者 | Gong Linji1,3; Xie Jiani1,3; Zhu Shuang1; Gu Zhanjun1,3; Zhao Yuliang1,2,3 |
| 刊名 | Acta physico-chimica sinica
 |
| 出版日期 | 2018 |
| 卷号 | 34期号:2页码:140-167 |
| 关键词 | Radiation therapy Nanoradiosensitizer Radiosensitization mechanism Nanomedicine |
| ISSN号 | 1000-6818 |
| DOI | 10.3866/pku.whxb201707174 |
| 通讯作者 | Gu zhanjun(zjgu@ihep.ac.cn) ; Zhao yuliang(zhaoyl@nanoctr.cn) |
| 英文摘要 | Radiation therapy kills tumor cells via focused high energy radiation, and has become one of the most common and effective clinical treatments for malignant tumors. however, some limitations restrict its clinical efficacy, including a requirement for elevated doses of radiation, side effects due to exposure of healthy tissue, and especially radioresistance of tumor cells. with the development of nanomedicine, multifunctional nanoradiosensitizers offer a new route to improve the efficiency of radiation therapy. in this paper, we summarize the main types of nanoradiosensitizers and their applications in radiation therapy, especially those that have currently entered clinical trials. we also summarize the main approaches to nanomaterials-based radiosensitization, and discuss the factors influencing their application. finally, the challenges and prospects of multifunctional nanoradiosensitizers are presented. |
| WOS关键词 | GADOLINIUM-BASED NANOPARTICLES ; IRON-OXIDE NANOPARTICLES ; CANCER RADIATION-THERAPY ; RAY COMPUTED-TOMOGRAPHY ; MESOPOROUS SILICA NANOPARTICLES ; RADIO-PHOTOTHERMAL THERAPY ; METAL-BASED NANOPARTICLES ; WALLED CARBON NANOTUBES ; NEAR-INFRARED WINDOW ; ONE-POT SYNTHESIS |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Physical |
| 语种 | 英语 |
| WOS记录号 | WOS:000423693100007 |
| 出版者 | PEKING UNIV PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177931 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Gu Zhanjun; Zhao Yuliang |
| 作者单位 | 1.Chinese Acad Sci, Inst High Energy Phys, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China 2.Natl Ctr Nanosci & Technol China, CAS Ctr Excellence Nanosci, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gong Linji,Xie Jiani,Zhu Shuang,et al. Application of multifunctional nanomaterials in tumor radiosensitization[J]. Acta physico-chimica sinica,2018,34(2):140-167. |
| APA | Gong Linji,Xie Jiani,Zhu Shuang,Gu Zhanjun,&Zhao Yuliang.(2018).Application of multifunctional nanomaterials in tumor radiosensitization.Acta physico-chimica sinica,34(2),140-167. |
| MLA | Gong Linji,et al."Application of multifunctional nanomaterials in tumor radiosensitization".Acta physico-chimica sinica 34.2(2018):140-167. |
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来源：高能物理研究所
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