Highly fluorescent chiral n-s-doped carbon dots from cysteine: affecting cellular energy metabolism
文献类型：期刊论文
| 作者 | Li, Feng1,4; Li, Yiye2,3; Yang, Xiao2,3; Han, Xuexiang2,3; Jiao, Yang1; Wei, Taotao5; Yang, Dayong4; Xu, Huaping1; Nie, Guangjun2,3 |
| 刊名 | Angewandte chemie-international edition
 |
| 出版日期 | 2018-02-23 |
| 卷号 | 57期号:9页码:2377-2382 |
| 关键词 | Carbon dots Cellular energy metabolism Chirality Glycolysis Green synthesis |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201712453 |
| 通讯作者 | Xu, huaping(xuhuaping@mail.tsinghua.edu.cn) ; Nie, guangjun(niegj@nanoctr.cn) |
| 英文摘要 | Cysteine-based chiral optically active carbon dots (cds) and their effects on cellular energy metabolism, which is vital for essential cellular functions, have been barely reported. a green and effective synthesis strategy for chiral n-s-doped cds (fluorescence quantum yield ca. 41.26%) based on hydrothermal treatment of l-or d-cysteine at as low as 60 degrees c has been developed. this suggested that cysteine was instable in aqueous solutions and acts as a warning for high-temperature synthesis of nanomaterials using cysteine as stabilizer. human bladder cancer t24 cells treated with l-cds showed up-regulated glycolysis, while d-cds had no similar effects. in contrast, no disturbance to the basal mitochondrial aerobic respiration of t24 cells was caused by either chiral cd. |
| WOS关键词 | GRAPHENE QUANTUM DOTS ; SOLAR-DRIVEN CATALYSIS ; FACILE SYNTHESIS ; PHOTOLUMINESCENCE ; PHOTOSENSITIZERS ; NANOPARTICLES ; EMISSION ; NANODOTS ; NITROGEN ; THERAPY |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000425453300016 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2177978 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Xu, Huaping; Nie, Guangjun |
| 作者单位 | 1.Tsinghua Univ, Dept Chem, Key Lab Organ Optoelect & Mol Engn, Beijing 100084, Peoples R China 2.Natl Ctr Nanosci & Technol, CAS Ctr Excellence Nanosci, CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100190, Peoples R China 4.Tianjin Univ, Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Sch Chem Engn & Technol, Key Lab Syst Bioengn,Minist Educ, Tianjin 300072, Peoples R China 5.Chinese Acad Sci, Inst Biophys, Natl Lab Biomacromol, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Feng,Li, Yiye,Yang, Xiao,et al. Highly fluorescent chiral n-s-doped carbon dots from cysteine: affecting cellular energy metabolism[J]. Angewandte chemie-international edition,2018,57(9):2377-2382. |
| APA | Li, Feng.,Li, Yiye.,Yang, Xiao.,Han, Xuexiang.,Jiao, Yang.,...&Nie, Guangjun.(2018).Highly fluorescent chiral n-s-doped carbon dots from cysteine: affecting cellular energy metabolism.Angewandte chemie-international edition,57(9),2377-2382. |
| MLA | Li, Feng,et al."Highly fluorescent chiral n-s-doped carbon dots from cysteine: affecting cellular energy metabolism".Angewandte chemie-international edition 57.9(2018):2377-2382. |
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