Impact of titanium dioxide and fullerenol nanoparticles on caco-2 gut epithelial cells
文献类型：期刊论文
| 作者 | Yang, Shengmei1,2; Xiong, Fengxia2; Chen, Kui2; Chang, Yanan2; Bai, Xue2; Yin, Wenyan2; Gu, Weihong2; Wang, Qianyuan2; Li, Juan2; Chen, Guogang1 |
| 刊名 | Journal of nanoscience and nanotechnology
 |
| 出版日期 | 2018-04-01 |
| 卷号 | 18期号:4页码:2387-2393 |
| 关键词 | Caco-2 gut epithelial cells Titanium dioxide Fullerenol Nanoparticles |
| ISSN号 | 1533-4880 |
| DOI | 10.1166/jnn.2018.14540 |
| 通讯作者 | Li, juan() ; Chen, guogang() |
| 英文摘要 | The application of nano-products in the food industry increases the risk of people exposed to nanoparticles. titanium dioxide nanoparticles (t-nps) are typically and widely used in food field, while fullerenol nanoparticles (f-nps) have great promise to be used as food additives. therefore, it is necessary and important to understand the safety of t-nps and f-nps in foods. in the present study, caco-2 gut epithelial cell line was selected as a model to investigate the impact of t-nps and f-nps. the viability and proliferation of caco-2 gut epithelial cells incubated with different concentrations of t-nps and f-nps were observed. the results showed that the two kinds of nanoparticles did not induce cell death even lasting for 48 h. the results of apoptosis and dna damages in the cells indicated that both t-nps with 50 and 100 mu g/ml caused caco-2 gut epithelial cell apoptosis, but didn't cause significantly dna damages. f-nps with 200 and 500 mu g/ml concentrations also can induce cell apoptosis but no dna damage. |
| WOS关键词 | ROS |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| WOS类目 | Chemistry, Multidisciplinary ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter |
| 语种 | 英语 |
| WOS记录号 | WOS:000426050500016 |
| 出版者 | AMER SCIENTIFIC PUBLISHERS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2178005 |
| 专题 | 高能物理研究所 |
| 通讯作者 | Li, Juan; Chen, Guogang |
| 作者单位 | 1.ShiHezi Univ, Coll Food Sci, Shihezi 832000, Peoples R China 2.Chinese Acad Sci, Inst High Energy Phys, Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Shengmei,Xiong, Fengxia,Chen, Kui,et al. Impact of titanium dioxide and fullerenol nanoparticles on caco-2 gut epithelial cells[J]. Journal of nanoscience and nanotechnology,2018,18(4):2387-2393. |
| APA | Yang, Shengmei.,Xiong, Fengxia.,Chen, Kui.,Chang, Yanan.,Bai, Xue.,...&Chen, Guogang.(2018).Impact of titanium dioxide and fullerenol nanoparticles on caco-2 gut epithelial cells.Journal of nanoscience and nanotechnology,18(4),2387-2393. |
| MLA | Yang, Shengmei,et al."Impact of titanium dioxide and fullerenol nanoparticles on caco-2 gut epithelial cells".Journal of nanoscience and nanotechnology 18.4(2018):2387-2393. |
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来源：高能物理研究所
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