Dual-Sensitive Probe of 2-(Benzoacridin) ethyl-imidazole-1-carboxylate for Determination of Aliphatic Amine with Fluorescence and Online Atmospheric Pressure Chemical Ionization Mass Spectrometry Identification
文献类型：期刊论文
| 作者 | Fu Yan-Yan1; Li Xiao-Yan1; Sun Zhi-Wei2,3; Qin Xue-Qin1; Xia Lian1,2,3; Suo You-Rui2; Li Yu-Lin2; You Jin-Mao1,2 |
| 刊名 | chinese journal of analytical chemistry
 |
| 出版日期 | 2010 |
| 卷号 | 38期号:1页码:8-14 |
| 关键词 | High performance liquid chromatography/mass spectrometry Aliphatic amines 5-(2-Hydroxyethyl) benzoacridine 2-(Benzoacridin) ethyl-imidazole-1-carboxylate |
| ISSN号 | 0253-3820 |
| 中文摘要 | with comparison of three different methods for the marking of amines compound, an optimal derivatization method was selected. 5-(2-hydroxyethyl) benzoacridine (hba) reacts with coupling agent n, n'-carbonyldiimidazole (cdi) to form an activated amide intermediate 2-(benzoacridin) ethyl-imidazole-1-carboxylate(baeic). baeic, which is dual-sensitive probe, reacts preferably with amino compounds at 80 degrees c in the presence of 4-dimethylaminopyridine (dmap) catalyst in n, n-dimethylformamide (dmf) solvent to give the corresponding sensitively fluorescent derivatives with an excitation maximum at lambda(ex) of 280 nm and an emission maximum at lambda(em) of 510 nm. baeic-amine derivatives simultaneously exhibited high. ionization potential with percent ionization (changing from 5.62% to 58.08% in aqueous acetonitrile and from 2.14% to 56.58% in aqueous methanol. derivatives were not only sensitive to fluorescence but also to ms ionizable potential. the fluorescence detection limits(s/n = 3) were 0.12 - 0. 59 mu g/l. the online apci-ms detection limits were 1.9-14 mu g/l (s/n = 5) |
| 英文摘要 | with comparison of three different methods for the marking of amines compound, an optimal derivatization method was selected. 5-(2-hydroxyethyl) benzoacridine (hba) reacts with coupling agent n, n'-carbonyldiimidazole (cdi) to form an activated amide intermediate 2-(benzoacridin) ethyl-imidazole-1-carboxylate(baeic). baeic, which is dual-sensitive probe, reacts preferably with amino compounds at 80 degrees c in the presence of 4-dimethylaminopyridine (dmap) catalyst in n, n-dimethylformamide (dmf) solvent to give the corresponding sensitively fluorescent derivatives with an excitation maximum at lambda(ex) of 280 nm and an emission maximum at lambda(em) of 510 nm. baeic-amine derivatives simultaneously exhibited high. ionization potential with percent ionization (changing from 5.62% to 58.08% in aqueous acetonitrile and from 2.14% to 56.58% in aqueous methanol. derivatives were not only sensitive to fluorescence but also to ms ionizable potential. the fluorescence detection limits(s/n = 3) were 0.12 - 0. 59 mu g/l. the online apci-ms detection limits were 1.9-14 mu g/l (s/n = 5) |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | precolumn derivatization agent ; liquid-chromatography ; fluorometric detection ; waste-water ; acids ; chloride ; hplc |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000274371500002 |
| 公开日期 | 2011-12-13 |
| 源URL | [http://ir.nwipb.ac.cn//handle/363003/1772]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 作者单位 | 1.Qufu Normal Univ, Key Lab Life Organ Anal, Qufu 273165, Peoples R China 2.Chinese Acad Sci, NW Plateau Inst Biol, Xining 810001, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fu Yan-Yan,Li Xiao-Yan,Sun Zhi-Wei,et al. Dual-Sensitive Probe of 2-(Benzoacridin) ethyl-imidazole-1-carboxylate for Determination of Aliphatic Amine with Fluorescence and Online Atmospheric Pressure Chemical Ionization Mass Spectrometry Identification[J]. chinese journal of analytical chemistry,2010,38(1):8-14. |
| APA | Fu Yan-Yan.,Li Xiao-Yan.,Sun Zhi-Wei.,Qin Xue-Qin.,Xia Lian.,...&You Jin-Mao.(2010).Dual-Sensitive Probe of 2-(Benzoacridin) ethyl-imidazole-1-carboxylate for Determination of Aliphatic Amine with Fluorescence and Online Atmospheric Pressure Chemical Ionization Mass Spectrometry Identification.chinese journal of analytical chemistry,38(1),8-14. |
| MLA | Fu Yan-Yan,et al."Dual-Sensitive Probe of 2-(Benzoacridin) ethyl-imidazole-1-carboxylate for Determination of Aliphatic Amine with Fluorescence and Online Atmospheric Pressure Chemical Ionization Mass Spectrometry Identification".chinese journal of analytical chemistry 38.1(2010):8-14. |
入库方式： OAI收割
来源：西北高原生物研究所
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