Prediction of Deleterious SNPs in ABC Transporter Superfamily
文献类型：会议论文
| 作者 | Li YH(李艳红) ; Wang YH(王永华) ; Li Y(李燕) ; Yang L(杨凌) |
| 出版日期 | 2006-05-24 |
| 会议名称 | the 1st asia pacific issx meeting |
| 会议日期 | 2006-5-24 |
| 会议地点 | 韩国 |
| 页码 | 188/1 |
| 通讯作者 | 杨凌 |
| 中文摘要 | objective: to predict deleterious snps in abc transport superfamily. methods: based on a set of sequence-based features, i.e. 1, free energy; 2, volume; 3, hydrophobicity; 4, sift score; 5, normalized site entropy; 6, residue frequency, we have evaluated the predictive power of the six factors to differentiate between disease-causing snps and neutral changes. results and conclusion: we have identified many snps in abc superfimaly from dbsnp that are likely to be associated with disease and thus are good candidates for genotyping in association studies, which can be used to direct our functional assays. (supported by the dut-dicp scientific cooperation fund) |
| 学科主题 | 物理化学 |
| 语种 | 中文 |
| WOS记录号 | WOS:000242406900101 |
| 源URL | [http://159.226.238.44/handle/321008/112174]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 推荐引用方式 GB/T 7714 | Li YH,Wang YH,Li Y,et al. Prediction of Deleterious SNPs in ABC Transporter Superfamily[C]. 见:the 1st asia pacific issx meeting. 韩国. 2006-5-24. |
入库方式： OAI收割
来源：大连化学物理研究所
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