ssDNA-tailorable oxidase-mimicking activity of spinel MnCo2O4 for sensitive biomolecular detection in food sample
文献类型：期刊论文
| 作者 | Wang, Jianlong2; Suo, Yourui1 ; Hu, Na1; Wang, Rong2; Wang, Jing2; Liu, Xinnan2; Zhu, Wenxin2; Zhang, Wentao2; Chen, Kai2; Huang, Lunjie2
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| 刊名 | SENSORS AND ACTUATORS B-CHEMICAL
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| 出版日期 | 2018-09-15 |
| 卷号 | 269页码:87-95 |
| 关键词 | Activity Modulation Aptamer Biosensor Food Analysis Nanozyme Oxidase |
| ISSN号 | 0925-4005 |
| DOI | 10.1016/j.snb.2018.04.150 |
| 文献子类 | Article |
| 英文摘要 | Nanozyme technique with efficient modulating strategies is a promising tool for biocatalytic and biosensing applications, yet insights into target-responsive controllability of oxidase nanozymes remain largely unknown. In this contribution, we report a state-of-art oxidase-like and ssDNA-tunable nanozyme for biomolecular recognition. In detail, the spinel-type manganese cation substituted cobalt oxide (MnCo2O4) submicrospheres can imitate oxidase for efficiently catalytic oxidation of colorimetric substrate, superior to current metal oxide-based oxidase nanozymes. More importantly, the nanozyme activity of spinel MnCo2O4 can be reversibly inhibited by the attachment/detachment of aptamer strands on MnCo2O4 surface via the aptamer-target binding event, enabling a new colorimetric access for detecting biomolecules. Taking highly toxic ochratoxin A (OTA) as model molecule, we can selectively determine OTA in maize samples with a limit of detection (3 delta/S) of 0.08 ng/mL. The unique nanozyme property of spinel MnCo2O4, together with the principle of our approach, reveals the potential of ssDNA-tailorable oxidase nanozymes in biocatalytic and biosensing fields. (C) 2018 Elsevier B.V. All rights reserved. |
| WOS关键词 | PEROXIDASE-LIKE ACTIVITY ; COLORIMETRIC DETECTION ; NANOZYME ACTIVITY ; VISIBLE-LIGHT ; QUANTUM DOTS ; COCOA BEANS ; OCHRATOXIN ; NANOPARTICLES ; DNA ; APTASENSOR |
| WOS研究方向 | Chemistry ; Electrochemistry ; Instruments & Instrumentation |
| 语种 | 英语 |
| WOS记录号 | WOS:000433211100012 |
| 出版者 | ELSEVIER SCIENCE SA |
| 资助机构 | National Natural Science Foundation of China(21675127) ; Fundamental Research Funds for the Central Universities(2014YB093 ; Development Project of Qinghai Key Laboratory(2017-ZJ-Y10) ; 2452015257) |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/13792]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 通讯作者 | Wang, Jianlong |
| 作者单位 | 1.Chinese Acad Sci, Northwest Inst Plateau Biol, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Xining 810008, Qinghai, Peoples R China 2.Northwest A&F Univ, Coll Food Sci & Engn, Yangling 712100, Shaanxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Jianlong,Suo, Yourui,Hu, Na,et al. ssDNA-tailorable oxidase-mimicking activity of spinel MnCo2O4 for sensitive biomolecular detection in food sample[J]. SENSORS AND ACTUATORS B-CHEMICAL,2018,269:87-95. |
| APA | Wang, Jianlong.,Suo, Yourui.,Hu, Na.,Wang, Rong.,Wang, Jing.,...&Huang, Lunjie.(2018).ssDNA-tailorable oxidase-mimicking activity of spinel MnCo2O4 for sensitive biomolecular detection in food sample.SENSORS AND ACTUATORS B-CHEMICAL,269,87-95. |
| MLA | Wang, Jianlong,et al."ssDNA-tailorable oxidase-mimicking activity of spinel MnCo2O4 for sensitive biomolecular detection in food sample".SENSORS AND ACTUATORS B-CHEMICAL 269(2018):87-95. |
入库方式： OAI收割
来源：西北高原生物研究所
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