Due to the characteristics of MEMS gyroscope and the influence of the peripheral driving circuit, the MEMS gyroscope is easily affected by temperature and the accuracy is deteriorated. The compensation delay is caused by the complexity of the model in practical engineering applications. A second-order polynomial compensation model for temperature-divided regions is proposed by analyzing the mechanism of gyroscope zero-bias temperature drift. The Model first divides the temperature region of the gyroscope work, and then uses the least squares method to solve the parameters according to multiple linear regression analysis. Finally, the model was verified by experiments. The results show that the model can effectively reduce the drift temperature drift caused by temperature changes, which can reduce the temperature drift after compensation by 73.3%. © Springer Nature Switzerland AG 2019.