This study examines how tightness-looseness influence well-being at individual level and residential mobility as moderator. The sample comprised of 344 Chinese participants(aged 13 to 66), and the data were collected from the internet. Two important results were found. First, tightness-looseness was positively associated with the life satisfaction, job satisfaction and efficacy, but it was negatively associated with exhaustion. Tightness-looseness can predict job satisfaction, life satisfaction, exhaustion and efficacy. Second, Residential mobility partly moderated the relationship between tightness-looseness and well-being. Residential mobility had a moderating effect on the relationship between tightness-looseness and job satisfaction, tightness-looseness and exhaustion. © 2017 IEEE.