Neural indicators of perceptual variability of pain across species
文献类型:期刊论文
作者 | Hu, L.1,2; Iannetti, G. D.3,4 |
刊名 | PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA |
出版日期 | 2019-01-29 |
卷号 | 116期号:5页码:1782-1791 |
ISSN号 | 0027-8424 |
关键词 | pain individual variability gamma oscillations neural marker human |
DOI | 10.1073/pnas.1812499116 |
产权排序 | 1 |
文献子类 | Article |
英文摘要 | Individuals exhibit considerable and unpredictable variability in painful percepts in response to the same nociceptive stimulus. Previous work has found neural responses that, while not necessarily responsible for the painful percepts themselves, can still correlate well with intensity of pain perception within a given individual. However, there is no reliable neural response reflecting the variability in pain perception across individuals. Here, we use an electrophysiological approach in humans and rodents to demonstrate that brain oscillations in the gamma band [gamma-band event-related synchronization (gamma-ERS)] sampled by central electrodes reliably predict pain sensitivity across individuals. We observed a clear dissociation between the large number of neural measures that reflected subjective pain ratings at within-subject level but not across individuals, and gamma-ERS, which reliably distinguished subjective ratings within the same individual but also coded pain sensitivity across different individuals. Importantly, the ability of gamma-ERS to track pain sensitivity across individuals was selective because it did not track the between-subject reported intensity of nonpainful but equally salient auditory, visual, and nonnociceptive somatosensory stimuli. These results also demonstrate that graded neural activity related to within-subject variability should be minimized to accurately investigate the relationship between nociceptive-evoked neural activities and pain sensitivity across individuals. |
WOS关键词 | INDIVIDUAL-DIFFERENCES ; EEG RESPONSES ; HUMAN BRAIN ; C-FIBER ; A-DELTA ; OSCILLATIONS ; REFLECT ; STIMULATION ; SENSITIVITY ; MODULATION |
WOS研究方向 | Science & Technology - Other Topics |
语种 | 英语 |
出版者 | NATL ACAD SCIENCES |
WOS记录号 | WOS:000456944600051 |
源URL | [http://ir.psych.ac.cn/handle/311026/28338] |
专题 | 心理研究所_中国科学院心理健康重点实验室 |
通讯作者 | Hu, L.; Iannetti, G. D. |
作者单位 | 1.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing 100101, Peoples R China 2.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China 3.Ist Italiano Tecnol, Neurosci & Behav Lab, I-00161 Rome, Italy 4.UCL, Dept Neurosci Physiol & Pharmacol, London WC1E 6BT, England |
推荐引用方式 GB/T 7714 | Hu, L.,Iannetti, G. D.. Neural indicators of perceptual variability of pain across species[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,2019,116(5):1782-1791. |
APA | Hu, L.,&Iannetti, G. D..(2019).Neural indicators of perceptual variability of pain across species.PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA,116(5),1782-1791. |
MLA | Hu, L.,et al."Neural indicators of perceptual variability of pain across species".PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 116.5(2019):1782-1791. |
入库方式: OAI收割
来源:心理研究所
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