中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates

文献类型:期刊论文

作者Jiang, Lili1,2; Qiao, Kaini1,2,3; Sui, Danyang1,2,3; Zhang, Zhe1,2,3; Dong, Hao-Ming1,2,3
刊名PLOS ONE
出版日期2019-03-08
卷号14期号:3页码:12
ISSN号1932-6203
DOI10.1371/journal.pone.0213690
产权排序1
文献子类article
英文摘要

Understanding the critical features of the human brain at multiple time scales is vital for both normal development and disease research. A recently proposed method, the vertex-wise Index of Functional Criticality (vIFC) based on fMRI, has been testified as a sensitive neuroimaging marker to characterize critical transitions of human brain dynamics during Alzheimer's disease progression. However, it remains unclear whether vIFC in healthy brains is associated with neuropsychological and neurophysiological measurements. Using the Nathan Kline Institute/Rockland lifespan cross-sectional datasets and openfMRI single participant longitudinal datasets, we found consistent spatial patterns of vIFC across the entire cortical mantle: the inferior parietal and the precuneus exhibited high vIFC. On a time scale of years, we observed that vIFC increased with age in the left ventral posterior cingulate gyrus. On a time scale of days and weeks, vIFC demonstrated the capacity to identify a link between anxiety and pulse. These results showed that vIFC can serve as a useful neuroimaging marker for detecting physiological, behavioral, and neurodevelopmental transitions. Based on the criticality theory in nonlinear dynamics, the current vIFC study sheds new light on human brain studies from a nonlinear perspective and opens potential new avenues for normal and abnormal human brain studies.

WOS关键词HEART-RATE-VARIABILITY ; SURFACE-BASED ANALYSIS ; DEFAULT MODE ; ALZHEIMERS-DISEASE ; SLOWING-DOWN ; NETWORK ; FMRI ; CONNECTIVITY ; ORGANIZATION ; ARCHITECTURE
WOS研究方向Science & Technology - Other Topics
语种英语
出版者PUBLIC LIBRARY SCIENCE
WOS记录号WOS:000460640900047
源URL[http://ir.psych.ac.cn/handle/311026/28588]  
专题心理研究所_中国科学院行为科学重点实验室
通讯作者Jiang, Lili
作者单位1.CAS Key Lab Behav Sci, Inst Psychol, Beijing, Peoples R China
2.Chinese Acad Sci, Inst Psychol, Lifespan Connect & Behav Team, Beijing, Peoples R China
3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
推荐引用方式
GB/T 7714
Jiang, Lili,Qiao, Kaini,Sui, Danyang,et al. Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates[J]. PLOS ONE,2019,14(3):12.
APA Jiang, Lili,Qiao, Kaini,Sui, Danyang,Zhang, Zhe,&Dong, Hao-Ming.(2019).Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates.PLOS ONE,14(3),12.
MLA Jiang, Lili,et al."Functional criticality in the human brain: Physiological, behavioral and neurodevelopmental correlates".PLOS ONE 14.3(2019):12.

入库方式: OAI收割

来源:心理研究所

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