中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
The top-down regulation from the prefrontal cortex to insula via hypnotic aversion suggestions reduces smoking craving

文献类型:期刊论文

作者Li, Xiaoming1,2,3; Chen, Lijun2,3,4,5; Ma, Ru2,3; Wang, Haibao6; Wan, Li2,3; Wang, Ying2,3; Bu, Junjie2,3; Hong, Wei2,3; Lv, Wanwan2,3; Volistaedt-Klein, Sabine7
刊名HUMAN BRAIN MAPPING
出版日期2019-04-15
卷号40期号:6页码:1718-1728
ISSN号1065-9471
关键词EEG fMRI hypnosis nicotine addiction smoking craving
DOI10.1002/hbm.24483
产权排序3
文献子类whblqh@mail.ustc.edu.cn
英文摘要

Hypnosis has been shown to have treatment effects on nicotine addiction. However, the neural basis of these effects is poorly understood. This preliminary study investigated the neural mechanisms of hypnosis-based treatment on cigarette smoking, specifically, whether the hypnosis involves a top-down or bottom-up mechanism. Two groups of 45 smokers underwent a smoking aversion suggestion and viewed smoking-related pictures and neutral pictures. One group underwent functional magnetic resonance imaging scanning twice (control and hypnotic states), whereas the other group underwent two electroencephalograph sessions. Our study found that self-reported smoking craving decreased in both groups following hypnosis. Smoking cue-elicited activations in the right dorsal lateral prefrontal cortex (rDLPFC) and left insula (lI) and the functional connectivity between the rDLPFC and lI were increased in the hypnotic state compared with the control state. The delta band source waveforms indicated the activation from 390 to 862 ms at the rDLPFC and from 490 to 900 ms at the lI was significantly different between the smoking and neutral conditions in the hypnotic state, suggesting the activation in the rDLPFC preceded that in the lI. These results suggest that the decreased smoking craving via hypnotic aversion suggestions may arise from the top-down regulation of the rDLPFC to the lI. Our findings provide novel neurobiological evidence for understanding the therapeutic effects of hypnosis on nicotine addiction, and the prefrontal-insula circuit may serve as an imaging biomarker to monitor the treatment efficacy noninvasively.

WOS关键词UNDERSTANDING HYPNOSIS ; CUE-REACTIVITY ; NICOTINE ; CESSATION ; ANXIETY ; ADOLESCENTS ; INHIBITION ; DEPENDENCE ; ATTENTION ; ADDICTION
WOS研究方向Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
出版者WILEY
WOS记录号WOS:000460987100003
源URL[http://ir.psych.ac.cn/handle/311026/28622]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Wang, Haibao; Zhang, Xiaochu
作者单位1.Anhui Med Univ, Chaohu Clin Med Coll, Dept Med Psychol, Hefei, Anhui, Peoples R China
2.Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, Hefei, Anhui, Peoples R China
3.Univ Sci & Technol China, Sch Life Sci, Hefei 230027, Anhui, Peoples R China
4.Chinese Acad Sci, Inst Psychol, CAS Key Lab Behav Sci, Beijing, Peoples R China
5.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
6.Anhui Med Univ, Affiliated Hosp 1, Dept Radiol, Hefei, Anhui, Peoples R China
7.Heidelberg Univ, Cent Inst Mental Hlth, Dept Addict Behav & Addict Med, Mannheim, Germany
8.NIDA, Neuroimaging Res Branch, Intramural Res Program, NIH, Baltimore, MD USA
9.Tianjin Normal Univ, Acad Psychol & Behav, Tianjin, Peoples R China
10.Univ Sci & Technol China, Ctr Biomed Engn, Hefei, Anhui, Peoples R China
推荐引用方式
GB/T 7714
Li, Xiaoming,Chen, Lijun,Ma, Ru,et al. The top-down regulation from the prefrontal cortex to insula via hypnotic aversion suggestions reduces smoking craving[J]. HUMAN BRAIN MAPPING,2019,40(6):1718-1728.
APA Li, Xiaoming.,Chen, Lijun.,Ma, Ru.,Wang, Haibao.,Wan, Li.,...&Zhang, Xiaochu.(2019).The top-down regulation from the prefrontal cortex to insula via hypnotic aversion suggestions reduces smoking craving.HUMAN BRAIN MAPPING,40(6),1718-1728.
MLA Li, Xiaoming,et al."The top-down regulation from the prefrontal cortex to insula via hypnotic aversion suggestions reduces smoking craving".HUMAN BRAIN MAPPING 40.6(2019):1718-1728.

入库方式: OAI收割

来源:心理研究所

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