An intracellular diamine oxidase triggered hyperpolarized Xe-129 magnetic resonance biosensor
文献类型：期刊论文
| 作者 | Zhou, Xin; Ye, Chaohui; Liu, Maili; Yang, Yunhuang; Jiang, Weiping; Yuan, Yaping; Zhao, Longhui; Zeng, QingBin; Zhang, Xiaoxiao; Luo, Qing |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2018-12-18 |
| 卷号 | 54期号:97页码:5 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c8cc07822j |
| 英文摘要 | Here, a novel method was developed for suppressing Xe-129 signals in cucurbit[6]uril (CB6) until the trigger is activated by a specific enzyme. Due to its noncovalent interactions with amino-groups and CB6, putrescine dihydrochloride (Put) was chosen for blocking interactions between Xe-129 and CB6. Upon adding diamine oxidase (DAO), Put was released from CB6 and a Xe-129@CB6 Hyper-CEST signal emerged. This proposed Xe-129 biosensor was then tested in small intestinal villus epithelial cells. |
| WOS关键词 | FLUORESCENT DYE DISPLACEMENT ; HOST-GUEST COMPLEXATION ; ENZYME-ACTIVITY ; SATURATION-TRANSFER ; CONTRAST AGENT ; PARACEST MRI ; DAO ACTIVITY ; NMR ; XENON ; PH |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000452111000004 |
| 源URL | [http://ir.wipm.ac.cn/handle/112942/13442]  |
| 专题 | 中国科学院武汉物理与数学研究所 |
| 通讯作者 | Zhou, Xin |
| 作者单位 | Huazhong Univ Sci & Technol, State Key Lab Magnet Resonance & Atom & Mol Phys, Natl Ctr Magnet Resonance Wuhan,Wuhan Inst Phys &, Chinese Acad Sci,Wuhan Natl Lab Optoelect, Wuhan 430071, Hubei, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Xin,Ye, Chaohui,Liu, Maili,et al. An intracellular diamine oxidase triggered hyperpolarized Xe-129 magnetic resonance biosensor[J]. CHEMICAL COMMUNICATIONS,2018,54(97):5. |
| APA | Zhou, Xin.,Ye, Chaohui.,Liu, Maili.,Yang, Yunhuang.,Jiang, Weiping.,...&Zhang, Bin.(2018).An intracellular diamine oxidase triggered hyperpolarized Xe-129 magnetic resonance biosensor.CHEMICAL COMMUNICATIONS,54(97),5. |
| MLA | Zhou, Xin,et al."An intracellular diamine oxidase triggered hyperpolarized Xe-129 magnetic resonance biosensor".CHEMICAL COMMUNICATIONS 54.97(2018):5. |
入库方式： OAI收割
来源：武汉物理与数学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。