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Connectome-based individualized prediction of temperament trait scores

文献类型：期刊论文

作者Jiang, Rongtao1,2,3; Calhoun, Vince D.4,5,6,7; Zuo, Nianming1,2; Lin, Dongdong4,5; Li, Jin1,2; Fan, Lingzhong1,2; Qi, Shile1,2,3,4,5; Sun, Hailun1,2,3; Fu, Zening4,5; Song, Ming1,2
刊名NEUROIMAGE
出版日期2018-12-01
卷号183页码:366-374
ISSN号1053-8119
关键词Individualized prediction Temperament traits Functional connectivity Reward processing Temperament and character inventory (TCI)
DOI10.1016/j.neuroimage.2018.08.038
通讯作者Jiang, Tianzi(jiangtz@nlpr.ia.ac.cn) ; Sui, Jing(jing.sui@nlpr.ia.ac.cn)
英文摘要Temperament consists of multi-dimensional traits that affect various domains of human life. Evidence has shown functional connectome-based predictive models are powerful predictors of cognitive abilities. Putatively, individuals' innate temperament traits may be predictable by unique patterns of brain functional connectivity (FC) as well. However, quantitative prediction for multiple temperament traits at the individual level has not yet been studied. Therefore, we were motivated to realize the individualized prediction of four temperament traits (novelty seeking [NS], harm avoidance [HA], reward dependence [RD] and persistence [PS]) using whole-brain FC. Specifically, a multivariate prediction framework integrating feature selection and sparse regression was applied to resting-state fMRI data from 360 college students, resulting in 4 connectome-based predictive models that enabled prediction of temperament scores for unseen subjects in cross-validation. More importantly, predictive models for HA and NS could be successfully generalized to two relevant personality traits for unseen individuals, i.e., neuroticism and extraversion, in an independent dataset. In four temperament trait predictions, brain connectivities that show top contributing power commonly concentrated on the hippocampus, prefrontal cortex, basal ganglia, amygdala, and cingulate gyrus. Finally, across independent datasets and multiple traits, we show person's temperament traits can be reliably predicted using functional connectivity strength within frontal-subcortical circuits, indicating that human social and behavioral performance can be characterized by specific brain connectivity profile.
WOS关键词CHARACTER INVENTORY TCI ; BRAIN FUNCTIONAL CONNECTIVITY ; AVOIDANCE PERSONALITY-TRAITS ; NOVELTY SEEKING ; HARM AVOIDANCE ; CLONINGERS TEMPERAMENT ; PSYCHOBIOLOGICAL MODEL ; DECISION-MAKING ; REWARD-SEEKING ; AMYGDALA
资助项目China Natural Science Foundation[81471367] ; China Natural Science Foundation[61773380] ; Strategic Priority Research Program of the Chinese Academy of Sciences[XDBS01040100] ; NIH[1R56MH117107] ; NIH[P20GM103472] ; NIH[R01EB005846] ; NIH[1R01MH094524] ; National Science Foundation[1539067]
WOS研究方向Neurosciences & Neurology ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
出版者ACADEMIC PRESS INC ELSEVIER SCIENCE
WOS记录号WOS:000447750200032
资助机构China Natural Science Foundation ; Strategic Priority Research Program of the Chinese Academy of Sciences ; NIH ; National Science Foundation
源URL[http://ir.ia.ac.cn/handle/173211/22785]  
专题自动化研究所_脑网络组研究中心
通讯作者Jiang, Tianzi; Sui, Jing
作者单位1.Chinese Acad Sci, Inst Automat, Brainnetome Ctr, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Automat, Natl Lab Pattern Recognit, 95 Zhongguancun East Rd, Beijing 100190, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Mind Res Network, Albuquerque, NM 87106 USA
5.Lovelace Biomed & Environm Res Inst, Albuquerque, NM 87106 USA
6.Univ New Mexico, Dept Psychiat & Neurosci, Albuquerque, NM 87131 USA
7.Univ New Mexico, Dept Elect & Comp Engn, Albuquerque, NM 87131 USA
8.Univ Elect Sci & Technol China, Chengdu 610054, Sichuan, Peoples R China
9.Chinese Acad Sci, Ctr Excellence Brain Sci, Inst Automat, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Jiang, Rongtao,Calhoun, Vince D.,Zuo, Nianming,et al. Connectome-based individualized prediction of temperament trait scores[J]. NEUROIMAGE,2018,183:366-374.
APA Jiang, Rongtao.,Calhoun, Vince D..,Zuo, Nianming.,Lin, Dongdong.,Li, Jin.,...&Sui, Jing.(2018).Connectome-based individualized prediction of temperament trait scores.NEUROIMAGE,183,366-374.
MLA Jiang, Rongtao,et al."Connectome-based individualized prediction of temperament trait scores".NEUROIMAGE 183(2018):366-374.

入库方式： OAI收割

来源：自动化研究所

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