Self-Assembled Ti4+@Biospore Microspheres for Sensitive DNA Analysis
文献类型：期刊论文
| 作者 | Fei, Rui-Hua; Tan, Chen; Huang, Yue; Chen, Huan-Chun; Guo, Ai-Zhen; Wang, Hai-Lin; Hu, Yong-Gang |
| 刊名 | ACS APPLIED MATERIALS & INTERFACES
 |
| 出版日期 | 2017-03-01 |
| 卷号 | 9期号:40页码:34696-34705 |
| 关键词 | Spore Biomaterials Ti4++ Adsorption Dna Analysis |
| 英文摘要 | Ti4+ can be chemically adsorbed and assembled on the surface of the modified spore to form highly monodispersed Ti4+@spore microspheres. Moreover, we for the first time found that these biomicrospheres exhibit differential affinities toward ssDNA and dsDNA. As a principle-of-proof, we exploited the self-assembled Ti4+@spore microspheres for a hybridization analysis. Interestingly, in the hybridization analysis, residual ssDNA probes are selectively adsorbed on Ti4+@spore microspheres at pH 5.0 and then removed via centrifugation. By taking advantage of this property, the signal-to-noise ratio for DNA analysis was considerably increased by reducing the noise caused by the residual ssDNA probes. The proposed method features easy operation, high specificity, and sensitivity and thus exhibits potential for further applications on DNA biosensing. |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/39410]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Fei, Rui-Hua,Tan, Chen,Huang, Yue,et al. Self-Assembled Ti4+@Biospore Microspheres for Sensitive DNA Analysis[J]. ACS APPLIED MATERIALS & INTERFACES,2017,9(40):34696-34705. |
| APA | Fei, Rui-Hua.,Tan, Chen.,Huang, Yue.,Chen, Huan-Chun.,Guo, Ai-Zhen.,...&Hu, Yong-Gang.(2017).Self-Assembled Ti4+@Biospore Microspheres for Sensitive DNA Analysis.ACS APPLIED MATERIALS & INTERFACES,9(40),34696-34705. |
| MLA | Fei, Rui-Hua,et al."Self-Assembled Ti4+@Biospore Microspheres for Sensitive DNA Analysis".ACS APPLIED MATERIALS & INTERFACES 9.40(2017):34696-34705. |
入库方式： OAI收割
来源：生态环境研究中心
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