Solid phase synthesis of 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate
文献类型：期刊论文
| 作者 | Fu, MK; Wu, X; Ning, J; Li, JZ |
| 刊名 | CHINESE JOURNAL OF CHEMISTRY
 |
| 出版日期 | 2005 |
| 卷号 | 23期号:7页码:901-904 |
| 关键词 | 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 Benzoate Solid Phase Synthesis Silyl Ether Linker |
| 英文摘要 | To implement the solid phase synthesis of 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate, tert-butyldimethylsilylchloride was chosen for the first solution synthesis. Then a novel silyl chloride resin 1, achieved from hydroxymethyl polystyrene resin and dimethyldichlorosilane, was used successfully for the attachment of avermectin B-1 2. Through oxidation, amination formation, cleavage, and benzoate formation, resin bounded avermectin B-1 9 gave 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate 3. |
| 学科主题 | Chemistry |
| WOS研究方向 | Chemistry |
| WOS记录号 | WOS:000230195300020 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23374]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Fu, MK,Wu, X,Ning, J,et al. Solid phase synthesis of 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate[J]. CHINESE JOURNAL OF CHEMISTRY,2005,23(7):901-904. |
| APA | Fu, MK,Wu, X,Ning, J,&Li, JZ.(2005).Solid phase synthesis of 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate.CHINESE JOURNAL OF CHEMISTRY,23(7),901-904. |
| MLA | Fu, MK,et al."Solid phase synthesis of 4 ''-epi-methylamino-4 ''-deoxyavermectin B-1 benzoate".CHINESE JOURNAL OF CHEMISTRY 23.7(2005):901-904. |
入库方式： OAI收割
来源：生态环境研究中心
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