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Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities
文献类型：期刊论文
| 作者 | Zhu, XF; Zhang, HX; Lo, R |
| 刊名 | JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
 |
| 出版日期 | 2004 |
| 卷号 | 52期号:24页码:7272-7278 |
| 关键词 | Artichoke Cynara ScoL.mus L. Antimicrobial Activity Phenolic Compounds Caffeoylquinic Acid Derivatives Flavonoids |
| DOI | 10.1021/jf0490192 |
| 英文摘要 | A preliminary antimicrobial disk assay of chloroform, ethyl acetate, and n-butanol extracts of artichoke (Cynara scolymus L.) leaf extracts showed that the n-butanol fraction exhibited the most significant antimicrobial activities against seven bacteria species, four yeasts, and four molds. Eight phenolic compounds were isolated from the n-butanol soluble fraction of artichoke leaf extracts. On the basis of high-performance liquid chromatography/electrospray ionization mass spectrometry, tandem mass spectrometry, and nuclear magnetic resonance techniques, the structures of the isolated compounds were determined as the four caffeoylquinic acid derivatives, chlorogenic acid (1), cynarin (2), 3,5-di-O-caffeoylquinic acid (3), and 4,5-di-acaffeoylquinic acid (4), and the four flavonoids, luteolin-7-rutinoside (5), cynaroside (6), apigenin-7-rutinoside (7), and apigenin-7-O-beta-D-glucopyranoside (8), respectively. The isolated compounds were examined for their antimicrobial activities on the above microorganisms, indicating that all eight phenolic compounds showed activity against most of the tested organisms. Among them, chlorogenic acid, cynarin, luteolin-7-rutinoside, and cynaroside exhibited a relatively higher activity than other compounds; in addition, they were more effective against fungi than bacteria. The minimum inhibitory concentrations of these compounds were between 50 and 200 mug/mL. |
| WOS研究方向 | Agriculture ; Chemistry ; Food Science & Technology |
| WOS记录号 | WOS:000225358900013 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/23592]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Zhu, XF,Zhang, HX,Lo, R. Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities[J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,2004,52(24):7272-7278. |
| APA | Zhu, XF,Zhang, HX,&Lo, R.(2004).Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities.JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,52(24),7272-7278. |
| MLA | Zhu, XF,et al."Phenolic compounds from the leaf extract of artichoke (Cynara scolymus L.) and their antimicrobial activities".JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 52.24(2004):7272-7278. |
入库方式： OAI收割
来源：生态环境研究中心
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