Highly efficient synthesis of the mannose nonasaccharide of the N-glycan expressed on the HIV glycoprotein gp 120
文献类型:期刊论文
作者 | Zhu, YL; Kong, FZ |
刊名 | SYNLETT
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出版日期 | 2001 |
期号 | 8页码:1217-1220 |
关键词 | Regio- And Stereoselective Synthesis Mannopyranosyl Oligosaccharides |
英文摘要 | A highly concise and effective synthesis of the mannose nonasaccharide of the glycan expressed on the HIV protein gp 120 was achieved via TMSOTf promoted selective 6-glycosylation of a tetrasaccharide 4,6-diol acceptor with a pentasaccharide donor followed by deprotection. The pentasaccharide was constructed by selective 3,6-diglycosylation of 1,2-O-ethylidene-beta -D-mannopyranose with 2-O-acetyl-3,4,6-tri-O-benzoyl-alpha -D-mannopyranosyl-(1-->2)-3,4,6-tri-O-benzoyl-alpha -D-mannopyranosyl trichloroimidate while the tetrasaccharide was obtained by selective 3-O-glycosylation of allyl 4,6-O-benzilidene-alpha -D-mannopyranoside with 2,3,4,6-tetra-O-benzoyl-alpha -D-mannopyranosyl-(1-->2)-3,4,6-tri-O-benzoyl-alpha -D-mannopyranosyl -(1-->2)-3,4,6-tri-O-benzoyl-alpha -D-mannopyranosyl trichloroimidate. |
WOS记录号 | WOS:000170344200005 |
源URL | [http://ir.rcees.ac.cn/handle/311016/24100] ![]() |
专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
推荐引用方式 GB/T 7714 | Zhu, YL,Kong, FZ. Highly efficient synthesis of the mannose nonasaccharide of the N-glycan expressed on the HIV glycoprotein gp 120[J]. SYNLETT,2001(8):1217-1220. |
APA | Zhu, YL,&Kong, FZ.(2001).Highly efficient synthesis of the mannose nonasaccharide of the N-glycan expressed on the HIV glycoprotein gp 120.SYNLETT(8),1217-1220. |
MLA | Zhu, YL,et al."Highly efficient synthesis of the mannose nonasaccharide of the N-glycan expressed on the HIV glycoprotein gp 120".SYNLETT .8(2001):1217-1220. |
入库方式: OAI收割
来源:生态环境研究中心
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