Induction of immunomodulating cytokines by a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes
文献类型：期刊论文
| 作者 | Liu, MQ; Li, JZ; Kong, FZ; Lin, JY; Gao, Y |
| 刊名 | IMMUNOPHARMACOLOGY
 |
| 出版日期 | 1998 |
| 卷号 | 40期号:3页码:187-198 |
| 关键词 | Lentinus Edodes Polysaccharide-peptide Complex Induction Of Cytokines |
| DOI | 10.1016/S0162-3109(98)00043-5 |
| 英文摘要 | The immunomodulating effect of a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes (LE) was studied for elucidation of the mechanism of augmentation of cell-mediated immunity. RNA samples were isolated from the untreated and treated murine splenocytes and human peripheral blood mononuclear cells. RT-PCR was used to analyze the cytokine gene expression and bioassay was used to analyze the cytokine production. By administration of LE, the expression levels of IL-2 and TNF-alpha genes were augmented in the treated murine spleen mononuclear cells and human peripheral blood mononuclear cells. The production of IL-2 were augmented in the treated murine spleen mononuclear cells, and the production of TNF-alpha were augmented in the treated murine peritoneal exudate macrophages. The production of IL2 and TNF-alpha were augmented in the treated human peripheral blood mononuclear cells. These results suggest that LE may induce Th immune responses. (C) 1998 Elsevier Science B.V. All rights reserved. |
| WOS研究方向 | Immunology ; Pharmacology & Pharmacy |
| WOS记录号 | WOS:000077188800003 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/24295]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Liu, MQ,Li, JZ,Kong, FZ,et al. Induction of immunomodulating cytokines by a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes[J]. IMMUNOPHARMACOLOGY,1998,40(3):187-198. |
| APA | Liu, MQ,Li, JZ,Kong, FZ,Lin, JY,&Gao, Y.(1998).Induction of immunomodulating cytokines by a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes.IMMUNOPHARMACOLOGY,40(3),187-198. |
| MLA | Liu, MQ,et al."Induction of immunomodulating cytokines by a new polysaccharide-peptide complex from culture mycelia of Lentinus edodes".IMMUNOPHARMACOLOGY 40.3(1998):187-198. |
入库方式： OAI收割
来源：生态环境研究中心
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