Synthesis of a hexasaccharide acceptor corresponding to the reducing terminus of mycobacterial 3-O-methylmannose polysaccharide (MMP)
文献类型：期刊论文
| 作者 | Liao, WS; Lu, DP |
| 刊名 | CARBOHYDRATE RESEARCH
 |
| 出版日期 | 1996 |
| 卷号 | 296期号:1页码:171-182 |
| 关键词 | Synthesis Glycosylation 3-o-methylmannose Polysaccharide (Mmp) Mycobacterium |
| DOI | 10.1016/S0008-6215(96)00239-X |
| 英文摘要 | The title compound methyl O-(2,6-di-O-benzyl-3-O-methyl-alpha-D-mannopyranosyl)-[(1 --> 4)- O-(2,6-di-O-benzyl-3-O-methyl-alpha-D-mannopyranosyl)](4)-(1 --> 4)-2,6-di-O-benzyl-3-O-methyl-alpha-D- mannopyranoside (2) was synthesized in a blockwise manner, employing trichloroacetimidate (11) and (20) as glycosyl donors. The strategy relies on the single-step preparation of the 3-O-methyl ethers (4) and (12) as starting materials. Since all intermediates contain one or more OCH3 groups, they are easily identified by NMR spectroscopy using the methyl proton signals, Compound 2 corresponds to the reducing terminal hexasaccharide of mycobacterial 3-O-methylmannose polysaccharide (MMP). MMP has the unusual property of stimulating the fatty acid synthetase multienzyme complex. Compound 2 can serve as a suitable glycosyl acceptor for the synthesis of extended fragments of MMP. (C) 1996 Elsevier Science-Ltd. |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| WOS记录号 | WOS:A1996WC08700010 |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/24378]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 推荐引用方式 GB/T 7714 | Liao, WS,Lu, DP. Synthesis of a hexasaccharide acceptor corresponding to the reducing terminus of mycobacterial 3-O-methylmannose polysaccharide (MMP)[J]. CARBOHYDRATE RESEARCH,1996,296(1):171-182. |
| APA | Liao, WS,&Lu, DP.(1996).Synthesis of a hexasaccharide acceptor corresponding to the reducing terminus of mycobacterial 3-O-methylmannose polysaccharide (MMP).CARBOHYDRATE RESEARCH,296(1),171-182. |
| MLA | Liao, WS,et al."Synthesis of a hexasaccharide acceptor corresponding to the reducing terminus of mycobacterial 3-O-methylmannose polysaccharide (MMP)".CARBOHYDRATE RESEARCH 296.1(1996):171-182. |
入库方式： OAI收割
来源：生态环境研究中心
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