Spectrum- and time-resolved endogenous multiphoton signals reveal quantitative differentiation of premalignant and malignant gastric mucosa.
文献类型：期刊论文
| 作者 | Chen, Tingai; Zheng, Wei; Yang, Chunxia; Li, Xl; Li, Hui; He, Xingzhen; Xia, Xianyuan |
| 刊名 | BIOMEDICAL OPTICS EXPRESS
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Early identification of premalignant and malignant gastric mucosa is crucial to decrease the incidence and mortality of stomach cancer. Spectrum- and time-resolved multiphoton microscopy are capable of providing not only structural but also biochemical information at the subcellular level. Based on this multidimensional imaging technique, we performed a systematic investigation on fresh human tissue specimens at the typical stages of gastriccarcinogenesis, including normal, chronic gastritis with erosion, chronic gastritis with intestinal metaplasia, and intestinal-type adenocarcinoma. The results demonstrate that this technique is available to characterize the three-dimensional subcellular morphological and biochemical properties of gastric mucosaand further provide quantitative indicators of different gastric disorders, by using endogenous contrast. With advances in multiphoton endoscopy, it has the potential to allow noninvasive, label-free, real-time histological and functional diagnosis of premalignant and malignant lesions of stomach in the future. (c) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14213]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Chen, Tingai,Zheng, Wei,Yang, Chunxia,et al. Spectrum- and time-resolved endogenous multiphoton signals reveal quantitative differentiation of premalignant and malignant gastric mucosa.[J]. BIOMEDICAL OPTICS EXPRESS,2018. |
| APA | Chen, Tingai.,Zheng, Wei.,Yang, Chunxia.,Li, Xl.,Li, Hui.,...&Xia, Xianyuan.(2018).Spectrum- and time-resolved endogenous multiphoton signals reveal quantitative differentiation of premalignant and malignant gastric mucosa..BIOMEDICAL OPTICS EXPRESS. |
| MLA | Chen, Tingai,et al."Spectrum- and time-resolved endogenous multiphoton signals reveal quantitative differentiation of premalignant and malignant gastric mucosa.".BIOMEDICAL OPTICS EXPRESS (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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