Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration
文献类型：期刊论文
| 作者 | J. Qian; W. Zheng; Ben Zhong Tang; W. Qin; P. Zhang; H. Li; Jacky W. Y. Lam; Y. Cai; Ryan T. K. Kwok |
| 刊名 | Chemical Science
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Reported here is a successful strategy for the design of ultrabright red luminogens with aggregation-induced emission (AIE) features, donor–acceptor structures, and intense charge transfer effects. These luminogens show no aggregation caused emission quenching in the solid state and have high quantum efficiency. They can be fabricated into AIE dots by a simple nanoprecipitation procedure. The AIE dots exhibit high brightness, a large Stokes shift, good biocompatibility, satisfactory photostability, and a high two-photon absorption cross section. The AIE dots can be utilized as highly efficient fluorescent probes for in vivo deep-tissue imaging by a two-photon technique, which outperforms the one-photon technique under the same experimental conditions, in terms of penetration depth and image contrast. This is the first report of using highly emissive AIE dots for the accurate measurement of capillary diameters in mouse ears. Such a strategy sheds light on the development of efficient solid state red/NIR emitters for biological applications. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14225]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | J. Qian,W. Zheng,Ben Zhong Tang,et al. Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration[J]. Chemical Science,2018. |
| APA | J. Qian.,W. Zheng.,Ben Zhong Tang.,W. Qin.,P. Zhang.,...&Ryan T. K. Kwok.(2018).Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration.Chemical Science. |
| MLA | J. Qian,et al."Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration".Chemical Science (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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