An Approach for Noninvasive Blood Glucose Monitoring Based on Bioimpedance Difference Considering Blood Volume Pulsation
文献类型：期刊论文
| 作者 | Zedong Nie; Yuhang Liu; Lei Wang; Yang Hao; Jingzhen Li; Tobore Igbe |
| 刊名 | IEEE Access
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Noninvasive blood glucose monitoring (NBGM) provides a promising solution for patients with diabetes with the advantages of painless and continuous monitoring. To better characterize the response of glucose to radio-frequency (RF) signals at low frequencies, the conductivity and relative permittivity of aqueous solutions with different glucose concentrations were obtained by the use of an impedance analyzer in the frequency range of 1 kHz to 1 MHz. Furthermore, considering the blood volume pulsation in cardiac cycle, a new approach based on measuring bioimpedance was presented for NBGM in this paper. For this purpose, an inhomogeneous arm model, which consists of three tissue layers (i.e., blood, blood vessel, and other relevant tissues), was proposed to validate the aforementioned approach. Furthermore, the measurements were carried out by means of in vitro experiment and in vivo studies, respectively. The results showed that as the glucose concentration increased, the conductivity of aqueous solutions decreased when the frequency of RF signal was below 1 MHz. However, the relative permittivity was almost insensitive to glucose concentration. The simulation result of the arm model showed that as the glucose concentration increased, the bioimpedance difference of blood volume decreased. This was supported by both in vitro and in vivo experiments. We therefore suggest that the proposed approach for NBGM has potentials in practical applications. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14257]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Zedong Nie,Yuhang Liu,Lei Wang,et al. An Approach for Noninvasive Blood Glucose Monitoring Based on Bioimpedance Difference Considering Blood Volume Pulsation[J]. IEEE Access,2018. |
| APA | Zedong Nie,Yuhang Liu,Lei Wang,Yang Hao,Jingzhen Li,&Tobore Igbe.(2018).An Approach for Noninvasive Blood Glucose Monitoring Based on Bioimpedance Difference Considering Blood Volume Pulsation.IEEE Access. |
| MLA | Zedong Nie,et al."An Approach for Noninvasive Blood Glucose Monitoring Based on Bioimpedance Difference Considering Blood Volume Pulsation".IEEE Access (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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