Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors
文献类型：期刊论文
| 作者 | Xiangqi Liu, Chen Ye, Xiaoqing Li, Naiyuan Cui, Tianzhun Wu, Shiyu Du, Qiuping Wei, Li Fu, Jiancheng Yin *, Cheng-Te Lin* |
| 刊名 | Materials
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Potassium (K+) ion is an important biological substance in the human body and plays a critical role in the maintenance of transmembrane potential and hormone secretion. Several detection techniques, including fluorescent, electrochemical, and electrical methods, have been extensively investigated to selectively recognize K+ ions. In this work, a highly sensitive and selective biosensor based on single-layer graphene has been developed for K+ ion detection under Van der Pauw measurement configuration. With pre-immobilization of guanine-rich DNA on the graphene surface, the graphene devices exhibit a very low limit of detection (≈1 nM) with a dynamic range of 1 nM–10 μM and excellent K+ ion specificity against other alkali cations, such as Na+ ions. The origin of K+ ion selectivity can be attributed to the fact that the formation of guanine-quadruplexes from guanine-rich DNA has a strong affinity for capturing K+ ions. The graphene-based biosensors with improved sensing performance for K+ ion recognition can be applied to health monitoring and early disease diagnosis. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14282]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Xiangqi Liu, Chen Ye, Xiaoqing Li, Naiyuan Cui, Tianzhun Wu, Shiyu Du, Qiuping Wei, Li Fu, Jiancheng Yin *, Cheng-Te Lin*. Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors[J]. Materials,2018. |
| APA | Xiangqi Liu, Chen Ye, Xiaoqing Li, Naiyuan Cui, Tianzhun Wu, Shiyu Du, Qiuping Wei, Li Fu, Jiancheng Yin *, Cheng-Te Lin*.(2018).Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors.Materials. |
| MLA | Xiangqi Liu, Chen Ye, Xiaoqing Li, Naiyuan Cui, Tianzhun Wu, Shiyu Du, Qiuping Wei, Li Fu, Jiancheng Yin *, Cheng-Te Lin*."Highly Sensitive and Selective Potassium Ion Detection Based on Graphene Hall Effect Biosensors".Materials (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。