High spatial resolution BOLD fMRI using simultaneous multislice excitation with echo-shifting gradient echo at 7 Tesla
文献类型：期刊论文
| 作者 | Rohan Dharmakumar; Xin Liu; Guoxi Xie; Shi Su; Na Lu; Lin Jia; Xiaojing Long; Chunxiang Jiang; Hang Zhang; Ye Li |
| 刊名 | Magnetic Resonance Imaging
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | We introduce an accelerated gradient echo (GRE) sequence combining simultaneous multislice excitation (SMS) with echo-shifting technique for high spatial resolution blood oxygen level dependent (BOLD) functional MRI (fMRI). The simulation was conducted to optimize scan parameters. To validate the feasibility of the proposed technique, the visual and motor task experiments were performed at 7.0 Tesla (T). The single-shot EPI sequence was also applied in comparison with the proposed technique. The simulation results showed that an optimized flip angle of 9° provided maximal BOLD contrast for our scanning scheme, allowing low power deposition and SMS acceleration factor of 5. Additionally, parallel acquisition imaging with acceleration factor of 2 was utilized, which allowed a total acceleration factor of 10 in volunteer study. The experiment results showed that geometric distortion-free BOLD images with voxel size of 1.0 × 1.0 × 2.5 mm3 were obtained. Significant brain activation was identified in both visual and motor task experiments, which were in accordance with previous investigations. The proposed technique has potential for high spatial resolution fMRI at ultra-high field because of its sufficient BOLD sensitivity as well as improved acquisition speed over conventional GRE-based techniques. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14359]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Rohan Dharmakumar,Xin Liu,Guoxi Xie,et al. High spatial resolution BOLD fMRI using simultaneous multislice excitation with echo-shifting gradient echo at 7 Tesla[J]. Magnetic Resonance Imaging,2018. |
| APA | Rohan Dharmakumar.,Xin Liu.,Guoxi Xie.,Shi Su., Na Lu.,...&Lijuan Zhang.(2018).High spatial resolution BOLD fMRI using simultaneous multislice excitation with echo-shifting gradient echo at 7 Tesla.Magnetic Resonance Imaging. |
| MLA | Rohan Dharmakumar,et al."High spatial resolution BOLD fMRI using simultaneous multislice excitation with echo-shifting gradient echo at 7 Tesla".Magnetic Resonance Imaging (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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