Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications
文献类型：期刊论文
| 作者 | Tsai, Chih-Hung; Liu, Hao-Li; Jan, Chen-Kai; Chang, Hsin-Yu; Huang, Sheng-Min; Li, Meng-Lin; Qiu, Weibao; Zheng, Hairong |
| 刊名 | IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Focused ultrasound phased array systems have attracted increased attention for brain therapy applications. However, such systems currently lack a direct and real-time method to intraoperatively monitor ultrasound pressure distribution for securing treatment. This study proposes a dual-mode ultrasoundphased array system design to support transmit/receive operations for concurrent ultrasound exposure and backscattered focal beam reconstruction through a spherically focused ultrasound array. A 256-channel ultrasound transmission system was used to transmit focused ultrasonic energy (full 256 channels), with an extended implementation of multiple-channel receiving function (up to 64 channels) using the same 256-channel ultrasound array. Acoherent backscatter-received beam formation algorithm was implemented to map the point spread function (PSF) and focal beam distribution under a free-field/transcranial environment setup, with the backscattering generated from a strong scatterer (a point reflector or a microbubble-perfused tube) or aweakly scattered tissue-mimicking graphite phantom. Our results showed that PSF and focal beam can be successfully reconstructed and visualized in free-field conditions and can also be transcranially reconstructed following skull-induced aberration correction. In vivo experiments were conducted to demonstrate its capability to preoperatively and semiquantitatively map a focal beam to guide blood-brain barrier opening. The proposed system may have potential for real-time guidance of ultrasound brain intervention, and may facilitate the design of a dual-mode ultrasound phased array for brain therapeutic applications. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14361]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Tsai, Chih-Hung,Liu, Hao-Li,Jan, Chen-Kai,et al. Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications[J]. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL,2018. |
| APA | Tsai, Chih-Hung.,Liu, Hao-Li.,Jan, Chen-Kai.,Chang, Hsin-Yu.,Huang, Sheng-Min.,...&Zheng, Hairong.(2018).Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications.IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL. |
| MLA | Tsai, Chih-Hung,et al."Design and Implementation of a Transmit/Receive Ultrasound Phased Array for Brain Applications".IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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