Atomic force microscopy methodology and AFMech Suite software for nanomechanics on heterogeneous soft materials
文献类型：期刊论文
| 作者 | Florian J. Stadler; Guanlin Tang; Chandra S. Biswas; Jinlai Zha; Shiguo Chen; Massimiliano Galluzzi |
| 刊名 | NATURE COMMUNICATIONS
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Atomic force microscopy has proven to be a valuable technique to characterize the mechanical and morphological properties of heterogeneous soft materials such as biological specimens in liquid environment. Here we propose a 3-step method in order to investigate biological specimens where heterogeneity hinder a quantitative characterization: (1) precise AFM calibration, (2) nano-indentation in force volume mode, (3) array of finite element simulations built from AFM indentation events. We combine simulations to determine internal geometries, multi-layer material properties, and interfacial friction. In order to easily perform this analysis from raw AFM data to simulation comparison, we propose a standalone software, AFMech Suite comprising five interacting interfaces for simultaneous calibration, morphology, adhesion, mechanical, and simulation analysis. We test the methodology on soft hydrogels with hard spherical inclusions, as a soft-matter model system. Finally, we apply the method on E. coli bacteria supported on soft/hard hydrogels to prove usefulness in biological field. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14411]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Florian J. Stadler,Guanlin Tang,Chandra S. Biswas,et al. Atomic force microscopy methodology and AFMech Suite software for nanomechanics on heterogeneous soft materials[J]. NATURE COMMUNICATIONS,2018. |
| APA | Florian J. Stadler,Guanlin Tang,Chandra S. Biswas,Jinlai Zha,Shiguo Chen,&Massimiliano Galluzzi.(2018).Atomic force microscopy methodology and AFMech Suite software for nanomechanics on heterogeneous soft materials.NATURE COMMUNICATIONS. |
| MLA | Florian J. Stadler,et al."Atomic force microscopy methodology and AFMech Suite software for nanomechanics on heterogeneous soft materials".NATURE COMMUNICATIONS (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。