Improved quantification of amide proton transfer effect with direct saturation- and magnetization transfer-correction in a glioma rat model at 3 Tesla
文献类型：会议论文
| 作者 | Wu Yin; Chen Yinsheng; Zhao Yiying; Yang Shasha; Zhao Jing; Chen Zhongping; Sun Phillip Zhe |
| 出版日期 | 2018 |
| 会议日期 | 2018年 |
| 会议地点 | 巴黎 |
| 英文摘要 | Quantification of in vivo APT effect with routine asymmetry analysis is problematic due to concomitant contributions. Herein, a steady-state CEST signal solution was utilized to estimate direct water saturation (DWS) to improve Z-spectral quantification in a pulsed-RF CEST imaging. Specifically, APT effect was measured from the DWS and magnetization transfer (MT)-corrected CEST signals in glioma rat brains post-chemoradiotherapy at 3 Tesla. The proposed method revealed significant APT signal difference among regions of control (3.13±0.38%), necrosis (3.95±0.31%) and tumor (4.56±0.34%), consistent with histological observations and superior than routine asymmetry analysis. |
| URL标识 | 查看原文 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14570]  |
| 专题 | 深圳先进技术研究院_医工所 |
| 推荐引用方式 GB/T 7714 | Wu Yin,Chen Yinsheng,Zhao Yiying,et al. Improved quantification of amide proton transfer effect with direct saturation- and magnetization transfer-correction in a glioma rat model at 3 Tesla[C]. 见:. 巴黎. 2018年. |
入库方式： OAI收割
来源：深圳先进技术研究院
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