Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration
文献类型：期刊论文
| 作者 | Yang Yang; Wang, Xuzhu; Shao Jundong; Mustafa Abd El Raouf; Xie Hanhan; Huang Hao; Wang Huaiyu; Paul K. Chu; Yu Xue-Feng; AbdelBasit M.AbdEl-Aal |
| 刊名 | Biomaterials
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | A near-infrared (NIR) light-triggered drug delivery platform is produced by incorporating SrCl2 and BP nanosheets (BPs) into poly(lactic-co-glycolic acid) (PLGA) for bone regeneration. The fabricated BP-SrCl2/PLGA microspheres show efficient NIR absorption and photothermal effects due to the BPs. The NIR-triggered release behavior of Sr2+ by flawing the PLGA shells is investigated and the microspheres exhibit excellent cell viability and biodegradability. Implantation of the BP-SrCl2/PLGA microspheres into a rat femoral defect demonstrates good tissue compatibility and excellent bone regeneration capacity under NIR light irradiation. Our study indicates that local release of Sr2+ at optimal time periods controlled by NIR irradiation improves bone regeneration significantly and this NIR-triggered drug delivery system composed of BPs is suitable for therapies requiring precise control at specific time. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14663]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 推荐引用方式 GB/T 7714 | Yang Yang,Wang, Xuzhu,Shao Jundong,et al. Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration[J]. Biomaterials,2018. |
| APA | Yang Yang.,Wang, Xuzhu.,Shao Jundong.,Mustafa Abd El Raouf.,Xie Hanhan.,...&Zhang Yufeng.(2018).Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration.Biomaterials. |
| MLA | Yang Yang,et al."Near-infrared light-triggered drug delivery system based on black phosphorus for in vivo bone regeneration".Biomaterials (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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