Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice.
文献类型：期刊论文
| 作者 | Fan, Xiujun; Zhang, Baozhen; Tan, Lunbo; Yu, Yan; Wang, Baobei; Chen, Zhilong; Han, Jinyu; Li, Mengxia; Chen, Jie; Xiao, Tianxia |
| 刊名 | THERANOSTICS
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | Rationale: The availability of therapeutics to treat pregnancy complications is severely lacking, mainly due to the risk of harm to the fetus. In placental malaria, Plasmodium falciparum-infected erythrocytes (IEs) accumulate in the placenta by adhering to chondroitin sulfate A (CSA) on the surfaces of trophoblasts. Based on this principle, we have developed a method for targeted delivery of payloads to the placenta using a synthetic placental CSA-binding peptide (plCSA-BP) derived from VAR2CSA, a CSA-binding protein expressed on IEs. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14686]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 推荐引用方式 GB/T 7714 | Fan, Xiujun,Zhang, Baozhen,Tan, Lunbo,et al. Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice.[J]. THERANOSTICS,2018. |
| APA | Fan, Xiujun.,Zhang, Baozhen.,Tan, Lunbo.,Yu, Yan.,Wang, Baobei.,...&Zhang, Jian.(2018).Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice..THERANOSTICS. |
| MLA | Fan, Xiujun,et al."Placenta-specific drug delivery by trophoblast-targeted nanoparticles in mice.".THERANOSTICS (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
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