Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice
文献类型：期刊论文
| 作者 | Yan Yu; Ya-Li Yang; Li-Feng Sun; Tian-Xia Xiao; Bao-Bei Wang; Pei-Gen Ren; Hui-Ru Tang; Jian V. Zhang |
| 刊名 | Reproductive Biology and Endocrinology
 |
| 出版日期 | 2018 |
| 文献子类 | 期刊论文 |
| 英文摘要 | DHEA treatment induced some aspects of PCOS in wild-type mice, such as increased body weight, elevated serum testosterone, increased number of small, cystic, atretic follicles, and absence of corpus luteum in ovaries. However, Gpr1 deficiency significantly attenuated the DHEA-induced weight gain and ovarian phenotype, improving steroidogenesis in ovaries and estradiol synthesis in cultured granulosa cells, partially through mTOR signaling. Conclusions |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.siat.ac.cn:8080/handle/172644/14693]  |
| 专题 | 深圳先进技术研究院_医药所 |
| 推荐引用方式 GB/T 7714 | Yan Yu,Ya-Li Yang,Li-Feng Sun,et al. Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice[J]. Reproductive Biology and Endocrinology,2018. |
| APA | Yan Yu.,Ya-Li Yang.,Li-Feng Sun.,Tian-Xia Xiao.,Bao-Bei Wang.,...&Jian V. Zhang.(2018).Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice.Reproductive Biology and Endocrinology. |
| MLA | Yan Yu,et al."Deficiency of Gpr1 improves steroid hormone abnormality in hyperandrogenized mice".Reproductive Biology and Endocrinology (2018). |
入库方式： OAI收割
来源：深圳先进技术研究院
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。